Sterol carrier protein
Sterol carrier proteins (also known as nonspecific lipid transfer proteins) is a family of proteins that transfer steroids and probably also phospholipids and gangliosides between cellular membranes.
 Sterol carrier protein 2 | |||||||||
| Identifiers | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Symbol | SCP2 | ||||||||
| Pfam | PF02036 | ||||||||
| InterPro | IPR003033 | ||||||||
| PROSITE | PDOC00092 | ||||||||
| SCOP2 | 1qnd / SCOPe / SUPFAM | ||||||||
| OPM superfamily | 135 | ||||||||
| OPM protein | 2cx7 | ||||||||
| |||||||||
These proteins are different from plant nonspecific lipid transfer proteins but structurally similar to small proteins of unknown function from Thermus thermophilus.
This domain is involved in binding sterols. The human sterol carrier protein 2 (SCP2) is a basic protein that is believed to participate in the intracellular transport of cholesterol and various other lipids.[1]
See also
References
- Johansson J, Wuthrich K, Szyperski T, Scheek S, Assmann G, Seedorf U (1993). "NMR determination of the secondary structure and the three-dimensional polypeptide backbone fold of the human sterol carrier protein 2". FEBS Lett. 335 (1): 18–26. doi:10.1016/0014-5793(93)80431-S. PMID 8243660. S2CID 9969358.
External links
- Sterol carrier proteins in SCOP
- SCP-2 sterol transfer family in Pfam
- UMich Orientation of Proteins in Membranes families/superfamily-144
- sterol+carrier+proteins at the US National Library of Medicine Medical Subject Headings (MeSH)
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