Steven M. Weinreb
Steven M. Weinreb (born May 10, 1941) is an American chemist and is a professor of chemistry at Pennsylvania State University in United States. Together with Steven Nahm, he developed the Weinreb ketone synthesis,[1] which allows for mono-addition of an organometallic reagent such as a Grignard reagent or organolithium reagent to an amide.
Steven M. Weinreb | |
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Born | May 10, 1941 |
Nationality | American |
Alma mater | Cornell University A.B. 1963 University of Rochester Ph.D. 1967 |
Known for | Weinreb ketone synthesis |
Scientific career | |
Fields | Organic chemistry Natural products synthesis |
Institutions | The Pennsylvania State University |
Doctoral advisor | Marshall D. Gates, Jr |
Weinreb received his PhD for work with Marshall Gates at the University of Rochester in 1967. After post-docs with Gilbert Stork and George H. Buchi, he worked at Fordham University. He joined the Pennsylvania State University in 1978, where he holds the Russell and Mildred Marker Professor of Natural Products Chemistry chair.
References
- Nahm, S.; Weinreb, S. M. (1981), "N-methoxy-n-methylamides as effective acylating agents", Tetrahedron Letters, 22: 3815, doi:10.1016/s0040-4039(01)91316-4
- Weinreb, Steven M. (1985). "Alkaloid total synthesis by intramolecular imino Diels-Alder cycloadditions". Accounts of Chemical Research. 18: 16. doi:10.1021/ar00109a004.
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