Syndromic testing

Syndromic testing is a process by which a physician simultaneously tests a patient for multiple pathogens with overlapping symptomology. This allows doctors to order one test to see if patients are suffering from any one of multiple causes, rather than having to order a test for each potential underlying reason for the illness. It can be used with patients that are immunosuppressed, in hospital environments that have limited testing assets, or patients that could be suffering from any number of or combination of reasons for a specific syndrome, such as respiratory distress, gastroenteritis,[1] bloodstream infections, or CNS infections.[2] The test uses multi-panel syndromic assays that allow the simultaneous detection of a number of agents, increasing the accuracy of tests for microbial agents.[3] The first multiplex panel for syndromic testing to be approved by the FDA received approval in 2008,[4][5] and since, panels for several potential pathogens have been approved.[6]

References
  1. Rifai, Nader (January 17, 2019). Clinical Microbiology Elsevier eBook on VitalSource. Elsevier Health Sciences. ISBN 9780323661188 – via Google Books.
  2. Couturier, Marc Roger; Bard, Jennifer Dien (September 7, 2019). "Direct-from-Specimen Pathogen Identification: Evolution of Syndromic Panels". Clinics in Laboratory Medicine. 39 (3): 433–451. doi:10.1016/j.cll.2019.05.005. PMC 7131637. PMID 31383267 – via PubMed.
  3. Advances in Molecular Pathology, E-Book 2018. Elsevier Health Sciences. October 9, 2018. ISBN 9780323639668 – via Google Books.
  4. Tang, Yi-Wei; Stratton, Charles W. (November 9, 2018). Advanced Techniques in Diagnostic Microbiology: Volume 2: Applications. Springer. ISBN 9783319951119 – via Google Books.
  5. Dien Bard, Jennifer; Alby, Kevin (March 26, 2018). "Point-Counterpoint: Meningitis/Encephalitis Syndromic Testing in the Clinical Laboratory". Journal of Clinical Microbiology. 56 (4). doi:10.1128/JCM.00018-18. PMC 5869827. PMID 29343540.
  6. Kirby, James E. (August 11, 2019). Advances and Trends in Clinical Microbiology: The Next 20 Years, An Issue of the Clinics in Laboratory Medicine E-book. Elsevier Health Sciences. ISBN 9780323682701 – via Google Books.


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