TBRG1

Transforming growth factor beta regulator 1 is a protein that in humans is encoded by the TBRG1 gene.[4][5][6]

TBRG1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2WZO
Identifiers
Aliases	TBRG1, NIAM, TB-5, transforming growth factor beta regulator 1
External IDs	OMIM: 610614 MGI: 1100877 HomoloGene: 18102 GeneCards: TBRG1
Gene location (Human) Chr. Chromosome 11 (human)[1] Band 11q24.2 Start 124,622,836 bp[1] End 124,635,926 bp[1]
RNA expression pattern More reference expression data
Gene ontology Molecular function • GO:0001948 protein binding Cellular component • cell nucleus Biological process • DNA replication • cell cycle • protein stabilization • cell cycle arrest • negative regulation of cell proliferation • protein localization to nucleoplasm Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	84897	21376
Ensembl	ENSG00000154144	ENSMUSG00000011114
UniProt	Q3YBR2	Q3UB74
RefSeq (mRNA)	NM_032811	NM_025289
RefSeq (protein)	NP_116200	NP_079565
Location (UCSC)	Chr 11: 124.62 – 124.64 Mb	n/a
PubMed search	[2]	[3]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000154144 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. Babalola GO, Schultz RM (Oct 1995). "Modulation of gene expression in the preimplantation mouse embryo by TGF-alpha and TGF-beta". Mol Reprod Dev. 41 (2): 133–9. doi:10.1002/mrd.1080410203. PMID 7654366. S2CID 84997218.
5. Tompkins VS, Hagen J, Frazier AA, Lushnikova T, Fitzgerald MP, di Tommaso A, Ladeveze V, Domann FE, Eischen CM, Quelle DE (Jan 2007). "A novel nuclear interactor of ARF and MDM2 (NIAM) that maintains chromosomal stability". J Biol Chem. 282 (2): 1322–33. doi:10.1074/jbc.M609612200. PMID 17110379.
6. "Entrez Gene: TBRG1 transforming growth factor beta regulator 1".

Further reading

• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries". DNA Res. 12 (2): 117–26. doi:10.1093/dnares/12.2.117. PMID 16303743.
• Tompkins V, Hagen J, Zediak VP, Quelle DE (2006). "Identification of novel ARF binding proteins by two-hybrid screening". Cell Cycle. 5 (6): 641–6. doi:10.4161/cc.5.6.2560. PMID 16582619.