TDRD3

Tudor domain-containing protein 3 is a protein that in humans is encoded by the TDRD3 gene.[5] It contains a Tudor domain and UBA protein domain and has three distinct Protein isoforms.

TDRD3
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1WJI, 2LTO, 3PMT, 3PNW, 3S6W
Identifiers
Aliases	TDRD3, tudor domain containing 3
External IDs	OMIM: 614392 MGI: 2444023 HomoloGene: 12771 GeneCards: TDRD3
Gene location (Human) Chr. Chromosome 13 (human)[1] Band 13q21.2 Start 60,396,457 bp[1] End 60,573,878 bp[1]
Gene location (Mouse) Chr. Chromosome 14 (mouse)[2] Band 14|14 E1 Start 87,416,639 bp[2] End 87,545,504 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • methylated histone binding • GO:0001105 transcription coactivator activity • chromatin binding • GO:0001948 protein binding • RNA binding Cellular component • cytoplasm • exon-exon junction complex • cell nucleus • nucleoplasm • Golgi apparatus • cytosol Biological process • regulation of nucleic acid-templated transcription • covalent chromatin modification • chromatin organization • positive regulation of nucleic acid-templated transcription Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	81550	219249
Ensembl	ENSG00000083544	ENSMUSG00000022019
UniProt	Q9H7E2	Q91W18
RefSeq (mRNA)	NM_001146070 NM_001146071 NM_030794	NM_001253755 NM_172605
RefSeq (protein)	NP_001139542 NP_001139543 NP_110421	NP_001240684 NP_766193
Location (UCSC)	Chr 13: 60.4 – 60.57 Mb	Chr 14: 87.42 – 87.55 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000083544 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000022019 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: TDRD3 tudor domain containing 3".

Further reading

• Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
• Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
• Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
• Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.