TESPA1

Thymocyte expressed, positive selection associated 1 is a protein that in humans is encoded by the TESPA1 gene.[4]

TESPA1
Identifiers
Aliases	TESPA1, KIAA0748, HSPC257, thymocyte expressed, positive selection associated 1
External IDs	OMIM: 615664 MGI: 1914846 HomoloGene: 106645 GeneCards: TESPA1
Gene location (Mouse) Chr. Chromosome 10 (mouse)[1] Band 10|10 D3 Start 130,322,870 bp[1] End 130,364,111 bp[1]
Gene ontology Molecular function • receptor binding Cellular component • COP9 signalosome • endoplasmic reticulum membrane • endoplasmic reticulum • membrane • cytoplasm Biological process • COP9 signalosome assembly • positive regulation of T cell differentiation in thymus • positive regulation of T cell receptor signaling pathway Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	9840	67596
Ensembl	ENSG00000135426	ENSMUSG00000034833
UniProt	A2RU30 E9PIT9	Q3U132
RefSeq (mRNA)	NM_001098815 NM_001136030 NM_001261844 NM_014796	NM_183264
RefSeq (protein)	NP_001092285 NP_001129502 NP_001248773 NP_055611 NP_001338077 NP_001338078 NP_001338079 NP_001338080 NP_001338081 NP_001338082 NP_001338083 NP_001338084	NP_899087
Location (UCSC)	n/a	Chr 10: 130.32 – 130.36 Mb
PubMed search	[2]	[3]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCm38: Ensembl release 89: ENSMUSG00000034833 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Entrez Gene: Thymocyte expressed, positive selection associated 1".

Further reading

• Fujimoto T, Matsuzaki H, Tanaka M, Shirasawa S (April 2013). "Tespa1 protein is phosphorylated in response to store-operated calcium entry". Biochemical and Biophysical Research Communications. 434 (1): 162–5. doi:10.1016/j.bbrc.2013.02.128. PMID 23541577.
• Matsuzaki H, Fujimoto T, Tanaka M, Shirasawa S (April 2013). "Tespa1 is a novel component of mitochondria-associated endoplasmic reticulum membranes and affects mitochondrial calcium flux". Biochemical and Biophysical Research Communications. 433 (3): 322–6. doi:10.1016/j.bbrc.2013.02.099. PMID 23501103.