TFIP11

Tuftelin-interacting protein 11 is a protein that in humans is encoded by the TFIP11 gene.[5][6][7]

TFIP11
Identifiers
Aliases	TFIP11, NTR1, Spp382, TIP39, bK445C9.6, hNtr1, tuftelin interacting protein 11, STIP, STIP-1
External IDs	OMIM: 612747 MGI: 1930075 HomoloGene: 40813 GeneCards: TFIP11
Gene location (Human) Chr. Chromosome 22 (human)[1] Band 22q12.1 Start 26,491,225 bp[1] End 26,512,505 bp[1]
Gene location (Mouse) Chr. Chromosome 5 (mouse)[2] Band 5|5 F Start 112,326,358 bp[2] End 112,338,073 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • GO:0001948 protein binding • nucleic acid binding Cellular component • cytoplasm • nuclear speck • catalytic step 2 spliceosome • U2-type post-mRNA release spliceosomal complex • nucleolus • spliceosomal complex • nuclear chromosome, telomeric region • cell nucleus • nucleoplasm • extracellular matrix Biological process • RNA processing • protection from non-homologous end joining at telomere • negative regulation of protein complex assembly • biomineral tissue development • mRNA processing • spliceosomal complex disassembly • negative regulation of protein binding • negative regulation of double-strand break repair via nonhomologous end joining • RNA splicing • negative regulation of DNA ligase activity • mRNA splicing, via spliceosome Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	24144	54723
Ensembl	ENSG00000100109	ENSMUSG00000029345
UniProt	Q9UBB9	Q9ERA6
RefSeq (mRNA)	NM_001008697 NM_001346857 NM_001346858 NM_001346859 NM_001346861 NM_001346862 NM_012143	NM_018783
RefSeq (protein)	NP_001008697 NP_001333786 NP_001333787 NP_001333788 NP_001333790 NP_001333791 NP_036275	NP_061253
Location (UCSC)	Chr 22: 26.49 – 26.51 Mb	Chr 5: 112.33 – 112.34 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

Interactions

TFIP11 has been shown to interact with Tuftelin.[5]{

References

1. GRCh38: Ensembl release 89: ENSG00000100109 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000029345 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Paine CT, Paine ML, Luo W, Okamoto CT, Lyngstadaas SP, Snead ML (Aug 2000). "A tuftelin-interacting protein (TIP39) localizes to the apical secretory pole of mouse ameloblasts". J Biol Chem. 275 (29): 22284–92. doi:10.1074/jbc.M000118200. PMID 10806191.
6. Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Bocher M, Blocker H, Bauersachs S, Blum H, Lauber J, Dusterhoft A, Beyer A, Kohrer K, Strack N, Mewes HW, Ottenwalder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (Mar 2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
7. "Entrez Gene: TFIP11 tuftelin interacting protein 11".

Further reading

• Dunham I, Shimizu N, Roe BA, et al. (1999). "The DNA sequence of human chromosome 22". Nature. 402 (6761): 489–95. doi:10.1038/990031. PMID 10591208.
• Zhang QH, Ye M, Wu XY, et al. (2001). "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells". Genome Res. 10 (10): 1546–60. doi:10.1101/gr.140200. PMC 310934. PMID 11042152.
• Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
• Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
• Jurica MS, Licklider LJ, Gygi SR, et al. (2002). "Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis". RNA. 8 (4): 426–39. doi:10.1017/S1355838202021088. PMC 1370266. PMID 11991638.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Collins JE, Goward ME, Cole CG, et al. (2003). "Reevaluating human gene annotation: a second-generation analysis of chromosome 22". Genome Res. 13 (1): 27–36. doi:10.1101/gr.695703. PMC 430954. PMID 12529303.
• Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
• Wen X, Lei YP, Zhou YL, et al. (2005). "Structural organization and cellular localization of tuftelin-interacting protein 11 (TFIP11)". Cell. Mol. Life Sci. 62 (9): 1038–46. doi:10.1007/s00018-005-4547-z. PMID 15868102.
• Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.