TIMM23

Mitochondrial import inner membrane translocase subunit Tim23 is an enzyme that in humans is encoded by the TIMM23 gene.[3][4]

TIMM23B
Identifiers
Aliases	TIMM23B, TIMM23, bA592B15.7, translocase of inner mitochondrial membrane 23 homolog B
External IDs	HomoloGene: 140621 GeneCards: TIMM23B
Gene location (Human) Chr. Chromosome 10 (human)[1] Band 10q11.23 Start 49,942,049 bp[1] End 49,974,850 bp[1]
RNA expression pattern More reference expression data
Gene ontology Molecular function • P-P-bond-hydrolysis-driven protein transmembrane transporter activity • molecular function • protein transmembrane transporter activity Cellular component • membrane • integral component of mitochondrial inner membrane • TIM23 mitochondrial import inner membrane translocase complex • integral component of membrane • mitochondrion • mitochondrial inner membrane • cellular component Biological process • protein import into mitochondrial matrix • intracellular protein transport • protein transport • biological process Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	100652748	n/a
Ensembl	ENSG00000204152	n/a
UniProt	Q5SRD1	n/a
RefSeq (mRNA)	NM_001290117 NM_001290118 NM_001365871	n/a
RefSeq (protein)	NP_001277046 NP_001277047 NP_001352800	n/a
Location (UCSC)	Chr 10: 49.94 – 49.97 Mb	n/a
PubMed search	[2]	n/a
Wikidata
View/Edit Human

See also

• Mitochondria Inner Membrane Translocase
• TIMM17A
• TIMM22
• TIMM44

References

1. GRCh38: Ensembl release 89: ENSG00000204152 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. Bauer MF, Gempel K, Reichert AS, Rappold GA, Lichtner P, Gerbitz KD, Neupert W, Brunner M, Hofmann S (Jul 1999). "Genetic and structural characterization of the human mitochondrial inner membrane translocase". J Mol Biol. 289 (1): 69–82. doi:10.1006/jmbi.1999.2751. PMID 10339406.
4. "Entrez Gene: TIMM23 translocase of inner mitochondrial membrane 23 homolog (yeast)".

Further reading

• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Guo Y, Cheong N, Zhang Z, et al. (2004). "Tim50, a component of the mitochondrial translocator, regulates mitochondrial integrity and cell death". J. Biol. Chem. 279 (23): 24813–25. doi:10.1074/jbc.M402049200. PMID 15044455.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Yamamoto H, Esaki M, Kanamori T, et al. (2002). "Tim50 is a subunit of the TIM23 complex that links protein translocation across the outer and inner mitochondrial membranes". Cell. 111 (4): 519–28. doi:10.1016/S0092-8674(02)01053-X. PMID 12437925. S2CID 18869447.
• Moro F, Sirrenberg C, Schneider HC, et al. (1999). "The TIM17.23 preprotein translocase of mitochondria: composition and function in protein transport into the matrix". EMBO J. 18 (13): 3667–75. doi:10.1093/emboj/18.13.3667. PMC 1171444. PMID 10393182.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.