TIPARP

TCDD-inducible poly [ADP-ribose] polymerase is an enzyme that in humans is encoded by the TIPARP gene.[5][6]

TIPARP
Identifiers
Aliases	TIPARP, ARTD14, PARP7, pART14, TCDD inducible poly(ADP-ribose) polymerase
External IDs	OMIM: 612480 MGI: 2159210 HomoloGene: 9167 GeneCards: TIPARP
Gene location (Human) Chr. Chromosome 3 (human)[1] Band 3q25.31 Start 156,673,235 bp[1] End 156,706,770 bp[1]
Gene location (Mouse) Chr. Chromosome 3 (mouse)[2] Band 3|3 E1 Start 65,528,410 bp[2] End 65,555,518 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • transferase activity • transferase activity, transferring glycosyl groups • metal ion binding • NAD+ ADP-ribosyltransferase activity • protein ADP-ribosylase activity Cellular component • cell nucleus Biological process • palate development • protein ADP-ribosylation • positive regulation of protein catabolic process • estrogen metabolic process • androgen metabolic process • kidney development • skeletal system morphogenesis • cellular response to organic cyclic compound • post-embryonic development • negative regulation of gene expression • female gonad development • vasculogenesis • nitrogen compound metabolic process • smooth muscle tissue development • platelet-derived growth factor receptor signaling pathway • face morphogenesis • haematopoiesis • response to 2,3,7,8-tetrachlorodibenzodioxine • protein auto-ADP-ribosylation • protein mono-ADP-ribosylation Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	25976	99929
Ensembl	ENSG00000163659	ENSMUSG00000034640
UniProt	Q7Z3E1	Q8C1B2
RefSeq (mRNA)	NM_001184717 NM_001184718 NM_015508	NM_178892
RefSeq (protein)	NP_001171646 NP_001171647 NP_056323	NP_849223
Location (UCSC)	Chr 3: 156.67 – 156.71 Mb	Chr 3: 65.53 – 65.56 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000163659 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000034640 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Katoh M, Katoh M (Jul 2003). "Identification and characterization of human TIPARP gene within the CCNL amplicon at human chromosome 3q25.31". Int J Oncol. 23 (2): 541–7. doi:10.3892/ijo.23.2.541. PMID 12851707.
6. "Entrez Gene: TIPARP TCDD-inducible poly(ADP-ribose) polymerase".

Further reading

• Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
• Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
• Ménisser-de Murcia J, Mark M, Wendling O, et al. (2001). "Early embryonic lethality in PARP-1 Atm double-mutant mice suggests a functional synergy in cell proliferation during development". Mol. Cell. Biol. 21 (5): 1828–32. doi:10.1128/MCB.21.5.1828-1832.2001. PMC 86747. PMID 11238919.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Lehner B, Sanderson CM (2004). "A protein interaction framework for human mRNA degradation". Genome Res. 14 (7): 1315–23. doi:10.1101/gr.2122004. PMC 442147. PMID 15231747.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
• Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.