TRAPPC4

Trafficking protein particle complex subunit 4 is a protein that in humans is encoded by the TRAPPC4 gene.[5][6]

TRAPPC4
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2J3T, 2JSN, 2ZMV
Identifiers
Aliases	TRAPPC4, HSPC172, PTD009, SBDN, SYNBINDIN, TRS23, CGI-104, trafficking protein particle complex 4, NEDESBA
External IDs	OMIM: 610971 MGI: 1926211 HomoloGene: 105453 GeneCards: TRAPPC4
Gene location (Human) Chr. Chromosome 11 (human)[1] Band 11q23.3 Start 119,018,763 bp[1] End 119,025,454 bp[1]
Gene location (Mouse) Chr. Chromosome 9 (mouse)[2] Band 9|9 A5.2 Start 44,403,698 bp[2] End 44,407,600 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • GO:0001948 protein binding • Rab guanyl-nucleotide exchange factor activity Cellular component • cytosol • Golgi apparatus • synaptic vesicle • synapse • dendrite • endoplasmic reticulum • Golgi stack • Golgi membrane • TRAPP complex Biological process • dendrite development • COPII vesicle coating • vesicle-mediated transport • ER to Golgi vesicle-mediated transport Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	51399	60409
Ensembl	ENSG00000280495 ENSG00000196655	ENSMUSG00000032112
UniProt	Q9Y296	Q9ES56
RefSeq (mRNA)	NM_016146 NM_001318486 NM_001318488 NM_001318489 NM_001318490 NM_001318492 NM_001318494	NM_021789
RefSeq (protein)	NP_001305415 NP_001305417 NP_001305418 NP_001305419 NP_001305421 NP_001305423 NP_057230	NP_068561
Location (UCSC)	Chr 11: 119.02 – 119.03 Mb	Chr 9: 44.4 – 44.41 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. ENSG00000196655 GRCh38: Ensembl release 89: ENSG00000280495, ENSG00000196655 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000032112 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Lai CH, Chou CY, Ch'ang LY, Liu CS, Lin W (Aug 2000). "Identification of Novel Human Genes Evolutionarily Conserved in Caenorhabditis elegans by Comparative Proteomics". Genome Res. 10 (5): 703–13. doi:10.1101/gr.10.5.703. PMC 310876. PMID 10810093.
6. "Entrez Gene: TRAPPC4 trafficking protein particle complex 4".

Further reading

• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Gavin AC, Bösche M, Krause R, et al. (2002). "Functional organization of the yeast proteome by systematic analysis of protein complexes". Nature. 415 (6868): 141–7. doi:10.1038/415141a. PMID 11805826. S2CID 4425555.
• Zhang QH, Ye M, Wu XY, et al. (2001). "Cloning and Functional Analysis of cDNAs with Open Reading Frames for 300 Previously Undefined Genes Expressed in CD34+ Hematopoietic Stem/Progenitor Cells". Genome Res. 10 (10): 1546–60. doi:10.1101/gr.140200. PMC 310934. PMID 11042152.
• Ethell IM, Hagihara K, Miura Y, et al. (2000). "Synbindin, a Novel Syndecan-2–Binding Protein in Neuronal Dendritic Spines". J. Cell Biol. 151 (1): 53–68. doi:10.1083/jcb.151.1.53. PMC 2189810. PMID 11018053.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.