TTYH3

Tweety family member 3 is a protein that in humans is encoded by the TTYH3 gene. [5]

TTYH3
Identifiers
Aliases	TTYH3, tweety family member 3
External IDs	OMIM: 608919 MGI: 1925589 HomoloGene: 18431 GeneCards: TTYH3
Gene location (Human) Chr. Chromosome 7 (human)[1] Band 7p22.3 Start 2,631,986 bp[1] End 2,664,802 bp[1]
Gene location (Mouse) Chr. Chromosome 5 (mouse)[2] Band 5|5 G2 Start 140,620,578 bp[2] End 140,649,031 bp[2]
Gene ontology Molecular function • chloride channel activity • intracellular calcium activated chloride channel activity • volume-sensitive chloride channel activity Cellular component • integral component of membrane • cell membrane • extracellular exosome • membrane • chloride channel complex Biological process • ion transmembrane transport • chloride transport • ion transport • chloride transmembrane transport • transport Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	80727	78339
Ensembl	ENSG00000136295	ENSMUSG00000036565
UniProt	Q9C0H2	Q6P5F7
RefSeq (mRNA)	NM_025250	NM_175274 NM_001308039 NM_001308040
RefSeq (protein)	NP_079526	NP_001294969 NP_780483
Location (UCSC)	Chr 7: 2.63 – 2.66 Mb	Chr 5: 140.62 – 140.65 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

Function

This gene encodes a member of the tweety family of proteins. Members of this family function as chloride anion channels. The encoded protein functions as a calcium(2+)-activated large conductance chloride(-) channel. [provided by RefSeq, Jul 2008].

References

1. GRCh38: Ensembl release 89: ENSG00000136295 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000036565 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: Tweety family member 3". Retrieved 2020-04-12.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.