UNKL

RING finger protein unkempt-like is a protein that in humans is encoded by the UNKL gene.[5]

UNKL
Identifiers
Aliases	UNKL, C16orf28, ZC3H5L, ZC3HDC5L, unkempt family like zinc finger, unk like zinc finger
External IDs	OMIM: 617463 MGI: 1921404 HomoloGene: 62673 GeneCards: UNKL
Gene location (Human) Chr. Chromosome 16 (human)[1] Band 16p13.3 Start 1,363,205 bp[1] End 1,414,751 bp[1]
Gene location (Mouse) Chr. Chromosome 17 (mouse)[2] Band 17|17 A3.3 Start 25,188,397 bp[2] End 25,234,443 bp[2]
Gene ontology Molecular function • metal ion binding • GO:0001948 protein binding • ubiquitin-protein transferase activity • transferase activity • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific Cellular component • cell nucleus • cytoplasm • cytosol Biological process • protein ubiquitination • protein polyubiquitination • regulation of transcription from RNA polymerase II promoter Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	64718	74154
Ensembl	ENSG00000059145	ENSMUSG00000015127
UniProt	Q9H9P5	Q5FWH2
RefSeq (mRNA)	NM_001037125 NM_001193388 NM_001193389 NM_001276414 NM_001367622 NM_001370526 NM_001372107	NM_001197024 NM_001290736 NM_028789 NM_001357876 NM_001357877
RefSeq (protein)	NP_001032202 NP_001180317 NP_001180318 NP_001263343 NP_001354551 NP_001357455 NP_001359036	NP_001183953 NP_001277665 NP_083065 NP_001344805 NP_001344806
Location (UCSC)	Chr 16: 1.36 – 1.41 Mb	Chr 17: 25.19 – 25.23 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000059145 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000015127 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: UNKL unkempt homolog (Drosophila)-like".

Further reading

• Mohler J, Weiss N, Murli S, et al. (1992). "The embryonically active gene, unkempt, of Drosophila encodes a Cys3His finger protein". Genetics. 131 (2): 377–88. PMC 1205012. PMID 1339381.
• Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.
• Daniels RJ, Peden JF, Lloyd C, et al. (2001). "Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16". Hum. Mol. Genet. 10 (4): 339–52. doi:10.1093/hmg/10.4.339. PMID 11157797.
• Venter JC, Adams MD, Myers EW, et al. (2001). "The sequence of the human genome". Science. 291 (5507): 1304–51. doi:10.1126/science.1058040. PMID 11181995.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Martin J, Han C, Gordon LA, et al. (2005). "The sequence and analysis of duplication-rich human chromosome 16". Nature. 432 (7020): 988–94. doi:10.1038/nature03187. PMID 15616553.
• Barrios-Rodiles M, Brown KR, Ozdamar B, et al. (2005). "High-throughput mapping of a dynamic signaling network in mammalian cells". Science. 307 (5715): 1621–5. doi:10.1126/science.1105776. PMID 15761153. S2CID 39457788.
• Oh JH, Yang JO, Hahn Y, et al. (2006). "Transcriptome analysis of human gastric cancer". Mamm. Genome. 16 (12): 942–54. doi:10.1007/s00335-005-0075-2. PMID 16341674. S2CID 69278.
• Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.