USP51

Ubiquitin carboxyl-terminal hydrolase 51 is an enzyme that in humans is encoded by the USP51 gene.[5][6]

USP51
Identifiers
Aliases	USP51, ubiquitin specific peptidase 51
External IDs	MGI: 3588217 HomoloGene: 71495 GeneCards: USP51
Gene location (Human) Chr. X chromosome (human)[1] Band Xp11.21 Start 55,484,616 bp[1] End 55,489,202 bp[1]
Gene location (Mouse) Chr. X chromosome (mouse)[2] Band X|X F3 Start 153,006,469 bp[2] End 153,009,416 bp[2]
Gene ontology Molecular function • thiol-dependent ubiquitin-specific protease activity • zinc ion binding • peptidase activity • cysteine-type peptidase activity • hydrolase activity • metal ion binding • chromatin binding • histone binding Cellular component • chromosome Biological process • protein deubiquitination • ubiquitin-dependent protein catabolic process • proteolysis • histone deubiquitination • regulation of response to DNA damage stimulus • regulation of cell cycle process • regulation of double-strand break repair via homologous recombination • regulation of double-strand break repair via nonhomologous end joining • DNA repair • cellular response to DNA damage stimulus Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	158880	635253
Ensembl	ENSG00000247746	ENSMUSG00000067215
UniProt	Q70EK9	B1AY15
RefSeq (mRNA)	NM_201286	NM_001137547
RefSeq (protein)	NP_958443	NP_001131019
Location (UCSC)	Chr X: 55.48 – 55.49 Mb	Chr X: 153.01 – 153.01 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000247746 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000067215 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Puente XS, Sanchez LM, Overall CM, Lopez-Otin C (Jul 2003). "Human and mouse proteases: a comparative genomic approach". Nat Rev Genet. 4 (7): 544–58. doi:10.1038/nrg1111. PMID 12838346.
6. "Entrez Gene: USP51 ubiquitin specific peptidase 51".

Further reading

• Ross MT, Grafham DV, Coffey AJ, et al. (2005). "The DNA sequence of the human X chromosome". Nature. 434 (7031): 325–37. doi:10.1038/nature03440. PMC 2665286. PMID 15772651.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Puente XS, López-Otín C (2004). "A genomic analysis of rat proteases and protease inhibitors". Genome Res. 14 (4): 609–22. doi:10.1101/gr.1946304. PMC 383305. PMID 15060002.
• Xie H, Diber A, Pollock S, et al. (2004). "Bridging expressed sequence alignments through targeted cDNA sequencing". Genomics. 83 (4): 572–6. doi:10.1016/j.ygeno.2003.07.003. PMID 15028280.
• Quesada V, Díaz-Perales A, Gutiérrez-Fernández A, et al. (2004). "Cloning and enzymatic analysis of 22 novel human ubiquitin-specific proteases". Biochem. Biophys. Res. Commun. 314 (1): 54–62. doi:10.1016/j.bbrc.2003.12.050. PMID 14715245.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Dias Neto E, Correa RG, Verjovski-Almeida S, et al. (2000). "Shotgun sequencing of the human transcriptome with ORF expressed sequence tags". Proc. Natl. Acad. Sci. U.S.A. 97 (7): 3491–6. doi:10.1073/pnas.97.7.3491. PMC 16267. PMID 10737800.