Unidimensional Fatigue Impact Scale

The Unidimensional Fatigue Impact Scale (U-FIS) is a disease-specific patient-reported outcome measure which measures the impact of multiple sclerosis related fatigue.[1] It is a 22-item unidimensional scale which is based on needs-based quality of life theory.[1]

Background

The U-FIS was developed by Galen Research and published in 2009.[1] It was derived from the Fatigue Impact Scale, a scale identified by the Multiple Sclerosis Council for Clinical Practice Guidelines “as the most appropriate for assessing the impact of MS-related fatigue on quality of life”.[2]

Data from the FIS went through Rasch analysis and additional items were added from interviews with multiple sclerosis patients. The U-FIS was then tested for validity via patient interviews and a validation survey.[1]

International Use

The U-FIS has been translated and validated into eight different language versions: Canadian English, Canadian French, German, Swedish, Italian, French, US English and Spanish.[3]

It has been recommended for use in determining fatigue impact by an independent meta analysis[4] and has also been utilized in a study investigating the role of neuroticism, perfectionism and depression in chronic fatigue syndrome.[5]

References
  1. Meads, DM; Doward, LC; McKenna, SP; Fisk, J; Twiss, J; Eckert, B (October 2009). "The development and validation of the Unidimensional Fatigue Impact Scale (U-FIS)". Multiple sclerosis (Houndmills, Basingstoke, England). 15 (10): 1228–38. doi:10.1177/1352458509106714. PMID 19556314.
  2. Mathiowetz, V (Jul–Aug 2003). "Test-retest reliability and convergent validity of the Fatigue Impact Scale for persons with multiple sclerosis". The American Journal of Occupational Therapy. 57 (4): 389–95. doi:10.5014/ajot.57.4.389. PMID 12911080.
  3. Doward LC, Meads DM, Fisk J, Twiss J, Hagell P, Oprandi NC, Grand'Maison F, Bhan V, Arbizu T, Kohlmann T, Brassat D, Eckert BJ, McKenna SP (2010). "International Development of the Unidimensional Fatigue Impact Scale (U-FIS)". Value in Health. 13 (4): 463–8. doi:10.1111/j.1524-4733.2010.00706.x. PMID 20230543.
  4. Elbers RG, Rietberg MB, van Wegen EE, Verhoef J, Kramer SF, Terwee CB, Kwakkel G (August 2012). "Self-report fatigue questionnaires in multiple sclerosis, Parkinson's disease and stroke: a systematic review of measurement properties". Quality of Life Research. 21 (6): 925–44. doi:10.1007/s11136-011-0009-2. PMC 3389599. PMID 22012025.
  5. Valero, S; Sáez-Francàs, N; Calvo, N; Alegre, J; Casas, M (October 2013). "The role of neuroticism, perfectionism and depression in chronic fatigue syndrome. A structural equation modeling approach". Comprehensive Psychiatry. 54 (7): 1061–7. doi:10.1016/j.comppsych.2013.04.015. PMID 23759150.


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