WSB1

WD repeat and SOCS box-containing protein 1 is a protein that in humans is encoded by the WSB1 gene.[5][6][7]

WSB1
Identifiers
AliasesWSB1, SWIP1, WSB-1, WD repeat and SOCS box containing 1
External IDsOMIM: 610091 MGI: 1926139 HomoloGene: 9218 GeneCards: WSB1
Gene location (Human)
Chr.Chromosome 17 (human)[1]
Band17q11.1Start27,294,076 bp[1]
End27,315,926 bp[1]
RNA expression pattern


More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

26118

78889

Ensembl

ENSG00000109046

ENSMUSG00000017677

UniProt

Q9Y6I7

O54927

RefSeq (mRNA)

NM_015626
NM_134264
NM_134265
NM_001348350

NM_001042565
NM_019653

RefSeq (protein)

NP_056441
NP_599027
NP_001335279

NP_001036030
NP_062627

Location (UCSC)Chr 17: 27.29 – 27.32 MbChr 11: 79.24 – 79.25 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

This gene encodes a member of the WD-protein subfamily. This protein shares a high sequence identity to mouse and chick proteins. It contains several WD-repeats spanning most of the protein and an SOCS box in the C-terminus. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.[7]

References

  1. GRCh38: Ensembl release 89: ENSG00000109046 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000017677 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Vasiliauskas D, Hancock S, Stern CD (Aug 1999). "SWiP-1: novel SOCS box containing WD-protein regulated by signalling centres and by Shh during development". Mech Dev. 82 (1–2): 79–94. doi:10.1016/S0925-4773(99)00014-3. PMID 10354473. S2CID 15357835.
  6. Kile BT, Schulman BA, Alexander WS, Nicola NA, Martin HM, Hilton DJ (Jun 2002). "The SOCS box: a tale of destruction and degradation". Trends Biochem Sci. 27 (5): 235–41. doi:10.1016/S0968-0004(02)02085-6. PMID 12076535.
  7. "Entrez Gene: WSB1 WD repeat and SOCS box-containing 1".

Further reading

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