ZBED6

Zinc finger, BED-type containing 6 is a protein that in humans is encoded by the ZBED6 gene.[4]

ZBED6
Identifiers
Aliases	ZBED6, MGR, zinc finger BED-type containing 6
External IDs	OMIM: 613512 MGI: 3828086 HomoloGene: 130066 GeneCards: ZBED6
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1q32.1 Start 203,795,714 bp[1] End 203,854,999 bp[1]
Gene ontology Molecular function • DNA binding • protein dimerization activity • metal ion binding • GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity • RNA polymerase II regulatory region sequence-specific DNA binding • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific Cellular component • nucleolus • cell nucleus Biological process • negative regulation of transcription, DNA-templated • regulation of transcription, DNA-templated • transcription, DNA-templated • regulation of transcription from RNA polymerase II promoter Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	100381270	667118
Ensembl	ENSG00000257315	ENSMUSG00000102049
UniProt	P86452	D2EAC2
RefSeq (mRNA)	NM_001174108	NM_001166552
RefSeq (protein)	NP_001167579	NP_001160024
Location (UCSC)	Chr 1: 203.8 – 203.85 Mb	n/a
PubMed search	[2]	[3]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000257315 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Entrez Gene: Zinc finger, BED-type containing 6". Retrieved 2012-03-15.

Further reading

• Markljung E, Jiang L, Jaffe JD, Mikkelsen TS, Wallerman O, Larhammar M, Zhang X, Wang L, Saenz-Vash V, Gnirke A, Lindroth AM, Barrés R, Yan J, Strömberg S, De S, Pontén F, Lander ES, Carr SA, Zierath JR, Kullander K, Wadelius C, Lindblad-Toh K, Andersson G, Hjälm G, Andersson L (Dec 2009). O'Rahilly S (ed.). "ZBED6, a novel transcription factor derived from a domesticated DNA transposon regulates IGF2 expression and muscle growth". PLOS Biology. 7 (12): e1000256. doi:10.1371/journal.pbio.1000256. PMC 2780926. PMID 20016685.
• Butter F, Kappei D, Buchholz F, Vermeulen M, Mann M (Apr 2010). "A domesticated transposon mediates the effects of a single-nucleotide polymorphism responsible for enhanced muscle growth". EMBO Reports. 11 (4): 305–11. doi:10.1038/embor.2010.6. PMC 2854606. PMID 20134481.
• Andersson L (2010). "Studying phenotypic evolution in domestic animals: a walk in the footsteps of Charles Darwin". Cold Spring Harbor Symposia on Quantitative Biology. 74: 319–25. doi:10.1101/sqb.2009.74.039. PMID 20375320.