ZDHHC4

Probable palmitoyltransferase ZDHHC4 is an enzyme that in humans is encoded by the ZDHHC4 gene.[5]

ZDHHC4
Identifiers
Aliases	ZDHHC4, ZNF374, zinc finger DHHC-type containing 4
External IDs	MGI: 1920131 HomoloGene: 10006 GeneCards: ZDHHC4
Gene location (Human) Chr. Chromosome 7 (human)[1] Band 7p22.1 Start 6,577,434 bp[1] End 6,589,374 bp[1]
Gene location (Mouse) Chr. Chromosome 5 (mouse)[2] Band 5|5 G2 Start 143,316,489 bp[2] End 143,329,256 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • transferase activity, transferring acyl groups • protein-cysteine S-palmitoyltransferase activity • transferase activity Cellular component • Golgi apparatus • membrane • integral component of membrane • endoplasmic reticulum • endoplasmic reticulum membrane Biological process • protein targeting to membrane • peptidyl-L-cysteine S-palmitoylation Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	55146	72881
Ensembl	ENSG00000136247	ENSMUSG00000001844
UniProt	Q9NPG8	Q9D6H5
RefSeq (mRNA)	NM_001134387 NM_001134388 NM_001134389 NM_018106	NM_028379 NM_001359445
RefSeq (protein)	NP_001127859 NP_001127860 NP_001127861 NP_060576 NP_001358221 NP_001358222 NP_001358223 NP_001358224 NP_001358225 NP_001358226 NP_001358227 NP_001358228	NP_082655 NP_001346374
Location (UCSC)	Chr 7: 6.58 – 6.59 Mb	Chr 5: 143.32 – 143.33 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

See also

• Chromosome 7 (human)
• Cytochrome c oxidase
• DHHC domain

References

1. GRCh38: Ensembl release 89: ENSG00000136247 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000001844 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: ZDHHC4 zinc finger, DHHC-type containing 4".

Further reading

• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Scherer SW, Cheung J, MacDonald JR, et al. (2003). "Human chromosome 7: DNA sequence and biology". Science. 300 (5620): 767–72. doi:10.1126/science.1083423. PMC 2882961. PMID 12690205.
• Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Grimsby S, Jaensson H, Dubrovska A, et al. (2005). "Proteomics-based identification of proteins interacting with Smad3: SREBP-2 forms a complex with Smad3 and inhibits its transcriptional activity". FEBS Lett. 577 (1–2): 93–100. doi:10.1016/j.febslet.2004.09.069. PMID 15527767. S2CID 82568.