ZFAND5

Zinc finger AN1-type containing 5 is a protein that in humans is encoded by the ZFAND5 gene. [5]

ZFAND5
Identifiers
Aliases	ZFAND5, ZA20D2, ZFAND5A, ZNF216, zinc finger AN1-type containing 5
External IDs	OMIM: 604761 MGI: 1278334 HomoloGene: 21215 GeneCards: ZFAND5
Gene location (Human) Chr. Chromosome 9 (human)[1] Band 9q21.13 Start 72,351,413 bp[1] End 72,365,235 bp[1]
Gene location (Mouse) Chr. Chromosome 19 (mouse)[2] Band 19 B|19 14.32 cM Start 21,272,278 bp[2] End 21,286,840 bp[2]
Gene ontology Molecular function • DNA binding • zinc ion binding • GO:0001948 protein binding • metal ion binding • molecular function Cellular component • cytoplasm • cellular component Biological process • fibroblast migration • skeletal system morphogenesis • platelet-derived growth factor receptor signaling pathway • face development • respiratory system process • vasculature development • in utero embryonic development • smooth muscle tissue development • biological process Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	7763	22682
Ensembl	ENSG00000107372	ENSMUSG00000024750
UniProt	O76080	O88878
RefSeq (mRNA)	NM_006007 NM_001102420 NM_001102421 NM_001278243 NM_001278244 NM_001278245	NM_009551
RefSeq (protein)	NP_001095890 NP_001095891 NP_001265172 NP_001265173 NP_001265174 NP_005998	NP_033577
Location (UCSC)	Chr 9: 72.35 – 72.37 Mb	Chr 19: 21.27 – 21.29 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000107372 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000024750 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: Zinc finger AN1-type containing 5". Retrieved 2020-04-12.

Further reading

• Huang J, Teng L, Li L, Liu T, Li L, Chen D, Xu LG, Zhai Z, Shu HB (April 2004). "ZNF216 Is an A20-like and IkappaB kinase gamma-interacting inhibitor of NFkappaB activation". J. Biol. Chem. 279 (16): 16847–53. doi:10.1074/jbc.M309491200. PMID 14754897.
• Hishiya A, Ikeda K, Watanabe K (2005). "A RANKL-inducible gene Znf216 in osteoclast differentiation". J. Recept. Signal Transduct. Res. 25 (3): 199–216. doi:10.1080/10799890500240781. PMID 16194934. S2CID 11227257.
• Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M, Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ, Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S, Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD, Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE, Hingorani AD (November 2009). "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip". Am. J. Hum. Genet. 85 (5): 628–42. doi:10.1016/j.ajhg.2009.10.014. PMC 2775832. PMID 19913121.
• Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S (October 2010). "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study". Diabetes Care. 33 (10): 2250–3. doi:10.2337/dc10-0452. PMC 2945168. PMID 20628086.
• He G, Sun D, Ou Z, Ding A (July 2012). "The protein Zfand5 binds and stabilizes mRNAs with AU-rich elements in their 3'-untranslated regions". J. Biol. Chem. 287 (30): 24967–77. doi:10.1074/jbc.M112.362020. PMC 3408148. PMID 22665488.