ZGPAT

Zinc finger CCCH-type with G patch domain-containing protein is a protein that in humans is encoded by the ZGPAT gene.[5][6]

ZGPAT
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4II1
Identifiers
Aliases	ZGPAT, GPATC6, GPATCH6, KIAA1847, ZC3H9, ZC3HDC9, ZIP, zinc finger CCCH-type and G-patch domain containing
External IDs	MGI: 2449939 HomoloGene: 41874 GeneCards: ZGPAT
Gene location (Human) Chr. Chromosome 20 (human)[1] Band 20q13.33 Start 63,707,465 bp[1] End 63,736,142 bp[1]
Gene location (Mouse) Chr. Chromosome 2 (mouse)[2] Band 2|2 H4 Start 181,364,928 bp[2] End 181,383,628 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity • GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding • sequence-specific DNA binding • DNA binding • GO:0001078, GO:0001214, GO:0001206 DNA-binding transcription repressor activity, RNA polymerase II-specific • GO:0001948 protein binding • metal ion binding • nucleic acid binding • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific Cellular component • cell nucleus • cell membrane Biological process • negative regulation of epidermal growth factor-activated receptor activity • negative regulation of transcription, DNA-templated • regulation of transcription, DNA-templated • negative regulation of transcription from RNA polymerase II promoter • transcription, DNA-templated Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	84619	229007
Ensembl	ENSG00000197114	ENSMUSG00000027582
UniProt	Q8N5A5	Q8VDM1
RefSeq (mRNA)	NM_181485 NM_001083113 NM_001195653 NM_001195654 NM_032527 NM_181484	NM_001048148 NM_144894
RefSeq (protein)	NP_001076582 NP_001182582 NP_001182583 NP_115916 NP_852150	NP_001041613 NP_659143
Location (UCSC)	Chr 20: 63.71 – 63.74 Mb	Chr 2: 181.36 – 181.38 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000197114 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000027582 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Ordway JM, Bedell JA, Citek RW, Nunberg A, Garrido A, Kendall R, Stevens JR, Cao D, Doerge RW, Korshunova Y, Holemon H, McPherson JD, Lakey N, Leon J, Martienssen RA, Jeddeloh JA (Nov 2006). "Comprehensive DNA methylation profiling in a human cancer genome identifies novel epigenetic targets". Carcinogenesis. 27 (12): 2409–23. doi:10.1093/carcin/bgl161. PMID 16952911.
6. "Entrez Gene: ZGPAT zinc finger, CCCH-type with G patch domain".

Further reading

• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.
• Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
• Rual JF, Hirozane-Kishikawa T, Hao T, et al. (2004). "Human ORFeome Version 1.1: A Platform for Reverse Proteomics". Genome Res. 14 (10B): 2128–35. doi:10.1101/gr.2973604. PMC 528929. PMID 15489335.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Deloukas P, Matthews LH, Ashurst J, et al. (2002). "The DNA sequence and comparative analysis of human chromosome 20". Nature. 414 (6866): 865–71. doi:10.1038/414865a. PMID 11780052.
• Nagase T, Nakayama M, Nakajima D, et al. (2001). "Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 8 (2): 85–95. doi:10.1093/dnares/8.2.85. PMID 11347906.