ZKSCAN1

Zinc finger protein with KRAB and SCAN domains 1 is a protein that in humans is encoded by the ZKSCAN1 gene.[5]

ZKSCAN1
Identifiers
Aliases	ZKSCAN1, 9130423L19Rik, KOX18, PHZ-37, ZNF139, ZNF36, ZSCAN33, zinc finger with KRAB and SCAN domains 1
External IDs	OMIM: 601260 MGI: 1921820 HomoloGene: 34523 GeneCards: ZKSCAN1
Gene location (Human) Chr. Chromosome 7 (human)[1] Band 7q22.1 Start 100,015,572 bp[1] End 100,041,689 bp[1]
Gene location (Mouse) Chr. Chromosome 5 (mouse)[2] Band 5|5 G2 Start 138,085,084 bp[2] End 138,107,822 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • GO:0001948 protein binding • nucleic acid binding • metal ion binding • DNA binding • GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific Cellular component • intracellular • cell nucleus Biological process • regulation of transcription, DNA-templated • transcription, DNA-templated • regulation of transcription from RNA polymerase II promoter Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	7586	74570
Ensembl	ENSG00000106261	ENSMUSG00000029729
UniProt	P17029	Q8BGS3
RefSeq (mRNA)	NM_001287054 NM_001287055 NM_003439 NM_001346579 NM_001346580 NM_001346581	NM_029869 NM_133906
RefSeq (protein)	NP_001273983 NP_001273984 NP_001333508 NP_001333509 NP_001333510 NP_003430	NP_084145 NP_598667
Location (UCSC)	Chr 7: 100.02 – 100.04 Mb	Chr 5: 138.09 – 138.11 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

See also

• Chromosome 7 (human)
• Krüppel associated box (KRAB) domain
• Zinc finger protein

References

1. GRCh38: Ensembl release 89: ENSG00000106261 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000029729 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: ZKSCAN1 zinc finger with KRAB and SCAN domains 1".

Further reading

• Huebner K, Druck T, Croce CM, Thiesen HJ (1991). "Twenty-seven nonoverlapping zinc finger cDNAs from human T cells map to nine different chromosomes with apparent clustering". Am. J. Hum. Genet. 48 (4): 726–40. PMC 1682948. PMID 2014798.
• Thiesen HJ (1991). "Multiple genes encoding zinc finger domains are expressed in human T cells". New Biol. 2 (4): 363–74. PMID 2288909.
• Rousseau-Merck MF, Duro D, Berger R, Thiesen HJ (1995). "Chromosomal localization of two KOX zinc finger genes on chromosome bands 7q21-q22". Ann. Genet. 38 (2): 81–4. PMID 7486829.
• Tommerup N, Vissing H (1995). "Isolation and fine mapping of 16 novel human zinc finger-encoding cDNAs identify putative candidate genes for developmental and malignant disorders". Genomics. 27 (2): 259–64. doi:10.1006/geno.1995.1040. PMID 7557990.
• Strausberg RL; Feingold EA; Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Scherer SW; Cheung J; MacDonald JR; et al. (2003). "Human Chromosome 7: DNA Sequence and Biology". Science. 300 (5620): 767–72. doi:10.1126/science.1083423. PMC 2882961. PMID 12690205.
• Jikuya H; Takano J; Kikuno R; et al. (2003). "Characterization of long cDNA clones from human adult spleen. II. The complete sequences of 81 cDNA clones". DNA Res. 10 (1): 49–57. doi:10.1093/dnares/10.1.49. PMID 12693554.
• Ota T; Suzuki Y; Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Gerhard DS; Wagner L; Feingold EA; et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Olsen JV; Blagoev B; Gnad F; et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.