ZMYND10

Zinc finger MYND domain-containing protein 10 is a protein that in humans is encoded by the ZMYND10 gene.[5][6]

ZMYND10
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2D8Q, 2DAN
Identifiers
Aliases	ZMYND10, BLU, CILD22, FLU, zinc finger MYND-type containing 10, DNAAF7
External IDs	OMIM: 607070 MGI: 2387863 HomoloGene: 9293 GeneCards: ZMYND10
Gene location (Human) Chr. Chromosome 3 (human)[1] Band 3p21.31 Start 50,341,110 bp[1] End 50,345,732 bp[1]
Gene location (Mouse) Chr. Chromosome 9 (mouse)[2] Band 9|9 F1 Start 107,547,298 bp[2] End 107,551,319 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • GO:0001948 protein binding • metal ion binding Cellular component • cytoplasm • centriolar satellite • cytoskeleton • microtubule organizing center • apical plasma membrane • cell membrane • membrane Biological process • outer dynein arm assembly • motile cilium assembly • inner dynein arm assembly • positive regulation of motile cilium assembly Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	51364	114602
Ensembl	ENSG00000004838	ENSMUSG00000010044
UniProt	O75800	Q99ML0
RefSeq (mRNA)	NM_001308379 NM_015896	NM_053253 NM_001364526 NM_001379079 NM_001379080
RefSeq (protein)	NP_001295308 NP_056980	NP_444483 NP_001351455 NP_001366008 NP_001366009
Location (UCSC)	Chr 3: 50.34 – 50.35 Mb	Chr 9: 107.55 – 107.55 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000004838 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000010044 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Agathanggelou A, Dallol A, Zochbauer-Muller S, Morrissey C, Honorio S, Hesson L, Martinsson T, Fong KM, Kuo MJ, Yuen PW, Maher ER, Minna JD, Latif F (Mar 2003). "Epigenetic inactivation of the candidate 3p21.3 suppressor gene BLU in human cancers". Oncogene. 22 (10): 1580–8. doi:10.1038/sj.onc.1206243. PMID 12629521.
6. "Entrez Gene: ZMYND10 zinc finger, MYND-type containing 10".

Further reading

• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
• Lerman MI, Minna JD (2000). "The 630-kb lung cancer homozygous deletion region on human chromosome 3p21.3: identification and evaluation of the resident candidate tumor suppressor genes. The International Lung Cancer Chromosome 3p21.3 Tumor Suppressor Gene Consortium". Cancer Res. 60 (21): 6116–33. PMID 11085536.
• Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
• Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Liu XQ, Chen HK, Zhang XS, et al. (2003). "Alterations of BLU, a candidate tumor suppressor gene on chromosome 3p21.3, in human nasopharyngeal carcinoma". Int. J. Cancer. 106 (1): 60–5. doi:10.1002/ijc.11166. PMID 12794757. S2CID 22730979.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Qiu GH, Tan LK, Loh KS, et al. (2004). "The candidate tumor suppressor gene BLU, located at the commonly deleted region 3p21.3, is an E2F-regulated, stress-responsive gene and inactivated by both epigenetic and genetic mechanisms in nasopharyngeal carcinoma". Oncogene. 23 (27): 4793–806. doi:10.1038/sj.onc.1207632. PMID 15122337.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
• Marsit CJ, Kim DH, Liu M, et al. (2005). "Hypermethylation of RASSF1A and BLU tumor suppressor genes in non-small cell lung cancer: implications for tobacco smoking during adolescence". Int. J. Cancer. 114 (2): 219–23. doi:10.1002/ijc.20714. PMID 15540210. S2CID 6691671.
• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
• Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
• Muzny DM, Scherer SE, Kaul R, et al. (2006). "The DNA sequence, annotation and analysis of human chromosome 3". Nature. 440 (7088): 1194–8. doi:10.1038/nature04728. PMID 16641997.