Acetyl-CoA C-myristoyltransferase

In enzymology, an acetyl-CoA C-myristoyltransferase (EC 2.3.1.155) is an enzyme that catalyzes the chemical reaction

myristoyl-CoA + acetyl-CoA 3-oxopalmitoyl-CoA + CoA
acetyl-CoA C-myristoyltransferase
Identifiers
EC number2.3.1.155
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain
Identifiers
SymbolNMT_C
PfamPF02799
InterProIPR022677

Thus, the two substrates of this enzyme are myristoyl-CoA and acetyl-CoA, whereas its two products are 3-oxopalmitoyl-CoA and CoA.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is myristoyl-CoA:acetyl-CoA C-myristoyltransferase.

References

    • Miyazawa S, Furuta S, Osumi T, Hashimoto T, Ui N (August 1981). "Properties of peroxisomal 3-ketoacyl-coA thiolase from rat liver". J. Biochem. Tokyo. 90 (2): 511–9. PMID 6117552.


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