Anthony Hollander

Anthony Hollander (born 4 February 1964) is Head of the Institute of Integrative Biology[1] at the University of Liverpool, having taken up the position in June 2014. The Institute lies at the heart of a thriving bio-medical-science campus in Liverpool and has integrated bioscience structures with internationally recognized expertise ranging from electrons to ecosystems. Its science serves several key societal themes including food security, health and welfare, diagnostics, biodiversity and conservation and biofuels.

Career

On 19 November 2008, whilst in his previous position as Professor of Rheumatology and Tissue Engineering at the University of Bristol where he was Head of School of Cellular and Molecular Medicine,[2] it was reported in the Lancet[3] that an artificially-grown organ had been successfully transplanted into a woman in Barcelona, Claudia Castillo, a breakthrough in which Hollander played a key role as the only stem cell scientist on the team. The team was led by Paolo Macchiarini who has been accused of research fraud. Subsequently the work has been criticised after several of the patients died and there have been calls for the paper to be retracted.[4] The transplant technique has been described as scientifically unfounded.[5]

In 2009, Biddy Baxter, the editor of the children's television programme Blue Peter published a selection of children's letters received by the Blue Peter team. Amongst them was a letter from Hollander who had written in 1973 that he knew how to save lives. He now says that he owes his career to Miss Baxter: "If her letter had shown any hint of ridicule or disbelief I might perhaps never have trained to become a medical scientist or been driven to achieve the impossible dream, and really make a difference to a human being's life."[6]

Hollander grew up in North West London, one of six children. He was a pupil at Christ's College Finchley and from there went to The University of Bath where he read for a degree in Pharmacology and graduated with First Class Honours in 1987. He then moved to The University of Bristol where he undertook his doctoral research in the field of cartilage degradation in arthritis. He was awarded his PhD in 1990.[7] He then moved to Montreal, Canada where he was a postdoctoral scientist at McGill University for three years, again studying cartilage degradation in arthritis. In 1993 he was awarded a three-year Fellowship from The Arthritis Research Campaign (now Arthritis Research UK)[8] to be based in The University of Sheffield where he was appointed as lecturer. He was promoted to Reader in 1999 and he was then appointed to his Chair at The University of Bristol in 2000. In 2010, The Times newspaper ranking of Britain's 100 most important scientists included him at number 39 on the list. He was elected as President of The International Cartilage Repair Society for the term of office May 2012 until September 2013.

Hollander is co-founder, Director and Chief Scientific Officer of Azellon Cell Therapeutics,[9] a University of Bristol spin-out company funded to undertake the first clinical trial of stem cells for the treatment of torn knee cartilage. The trial is underway with preliminary results expected in 2015.

References
  1. http://www.liv.ac.uk/integrative-biology/
  2. http://www.bris.ac.uk/cellmolmed/
  3. Lancet 2008 volume 372, pp2023-2030
  4. https://www.youtube.com/watch?v=tUfgvLN3vBg
  5. Delaere, P; Van Raemdonck, D (2016). "Tracheal replacement". J Thorac Dis. 8 (Suppl 2): S186-96. doi:10.3978/j.issn.2072-1439.2016.01.85. PMC 4775267. PMID 26981270.
  6. "Dear Blue Peter... I can save lives". BBC. 2009-01-27.
  7. Inflammation and joint damage in rhuematoid arthritis (1990). University of Bristol PhD thesis
  8. http://www.arthritisresearchuk.org
  9. http://www.azellonctx.com/
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