Bert W. O'Malley

Bert W. O’Malley is the Tom Thompson Distinguished Service Professor of Molecular and Cellular Biology and Chancellor at Baylor College of Medicine. A native of Pittsburgh, he has a bachelor's degree from the University of Pittsburgh (A&S 1959) and a M.D. from their School of Medicine (1963). He completed his residency at Duke University and spent four years at the National Institute of Health followed by four years serving as the Luscious Birch Professor and the director of the Reproductive Biology Center at Vanderbilt University. He then moved to Baylor as Professor and Chairman of Molecular and Cellular Biology.

O’Malley's work has been on the primary actions of steroid hormones and nuclear receptors. Bert elucidated the overall genetic transcriptional pathway of steroid and intracellular hormone action, discovered nuclear receptor(NR) coactivators (CoAs), discovered the functional 3-D structures CoA-NR complexes on DNA, and the critical roles for coactivators in physiology and diseases. He has published over 700 papers and holds 29 patents in the fields of gene regulation, molecular endocrinology and steroid receptors and transcriptional coactivators. His work on molecular mechanisms of steroid receptor coactivators has great relevance to genetic and reproductive diseases, disorders of metabolism and diabetes, myocardial infarct induced heart failure, and especially, cancers. He is considered as the 'father of molecular endocrinology' and has received over 65 national/international awards/prizes for his scientific achievements in this field.

He was awarded the National Medal of Science by U.S. President George W. Bush on September 29, 2008.[1]

O'Malley is a brother of the Pi Kappa Alpha fraternity and was initiated at the Gamma Sigma chapter at the University of Pittsburgh.

Honors and awards

References

  1. Templeton, David (2008-08-29). "Pitt graduate given highest science honor in the U.S." Pittsburgh Post-Gazette. Archived from the original on 2008-12-01. Retrieved 2008-08-29.
  2. "Ernst Schering Prize". Ernst Schering Foundation. Archived from the original on 18 January 2015. Retrieved 16 January 2015.
  3. Louisa Gross Horwitz Prize 2018
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