Clefamide

Clefamide (trade name Mebinol) is an antiprotozoal agent that was used to treat amoebiasis in the 1960s.[1] There is no evidence for any later use of the drug.

Clefamide

Clinical data
Trade names	Mebinol
ATC code	P01AC02 (WHO)
Identifiers
IUPAC name 2,2-Dichloro-N-(2-hydroxyethyl)-N-[[4-(4-nitrophenoxy)phenyl]methyl]
CAS Number	3576-64-5
PubChem CID	71819
ChemSpider	64843
UNII	4AZ2V8K4EK
KEGG	D07354
ChEMBL	ChEMBL1788400
CompTox Dashboard (EPA)	DTXSID30189296
ECHA InfoCard	100.020.631
Chemical and physical data
Formula	C17H16Cl2N2O5
Molar mass	399.22 g·mol^−1
3D model (JSmol)	Interactive image
SMILES ClC(Cl)C(=O)N(CCO)Cc2ccc(Oc1ccc(cc1)[N+]([O-])=O)cc2
InChI InChI=1S/C17H16Cl2N2O5/c18-16(19)17(23)20(9-10-22)11-12-1-5-14(6-2-12)26-15-7-3-13(4-8-15)21(24)25/h1-8,16,22H,9-11H2 Key:ODCUSWJXZDHLKV-UHFFFAOYSA-N
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References

1. Rodrigues LD, Jafferian PA, Vilella M, Costa AA, de Mello EB (November 1968). "[Comparative study on 3 amebicides: teclozine, clefamide and a combination of clefamide and iodo-chloro-oxyquinolines and streptomycin]". Hospital. 74 (5): 1563–73. PMID 5305335.