D-amino-acid N-acetyltransferase
In enzymology, a D-amino-acid N-acetyltransferase (EC 2.3.1.36) is an enzyme that catalyzes the chemical reaction
- acetyl-CoA + a D-amino acid CoA + an N-acetyl-D-amino acid
| D-amino-acid N-acetyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.3.1.36 | ||||||||
| CAS number | 37257-15-1 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Thus, the two substrates of this enzyme are acetyl-CoA and D-amino acid, whereas its two products are CoA and N-acetyl-D-amino acid.
This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acetyl-CoA:D-amino-acid N-acetyltransferase. Other names in common use include D-amino acid acetyltransferase, and D-amino acid-alpha-N-acetyltransferase. This enzyme participates in phenylalanine metabolism.
References
- Zenk MH, Schmitt J (1965). "Reinigung und Eigenschaften von Acetyl-CoA:D-Aminosaure-alpha-N-Acetyltransferase aus Hefe". Biochem. Z. 342: 54–65.
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