Dilazep

Dilazep is a vasodilator that acts as an adenosine reuptake inhibitor.[1]

Dilazep

Clinical data
Trade names	Comelian Kowa
AHFS/Drugs.com	International Drug Names
ATC code	C01DX10 (WHO)
Identifiers
IUPAC name 3-(4-{3-[(3,4,5-Trimethoxyphenyl)carbonyloxy]propyl}-1,4-diazepan-1-yl)propyl 3,4,5-trimethoxybenzoate
CAS Number	35898-87-4
PubChem CID	3074
IUPHAR/BPS	4717
ChemSpider	2965
UNII	F8KLC2BD5Z
KEGG	D07843
ChEMBL	ChEMBL126075
CompTox Dashboard (EPA)	DTXSID9045425
Chemical and physical data
Formula	C31H44N2O10
Molar mass	604.697 g·mol^−1
3D model (JSmol)	Interactive image
SMILES O=C(OCCCN2CCCN(CCCOC(=O)c1cc(OC)c(OC)c(OC)c1)CC2)c3cc(OC)c(OC)c(OC)c3
InChI InChI=1S/C31H44N2O10/c1-36-24-18-22(19-25(37-2)28(24)40-5)30(34)42-16-8-12-32-10-7-11-33(15-14-32)13-9-17-43-31(35)23-20-26(38-3)29(41-6)27(21-23)39-4/h18-21H,7-17H2,1-6H3 Key:QVZCXCJXTMIDME-UHFFFAOYSA-N
(verify)

It is used for the treatment of cardiopathy and renal disorders.[2]

See also

• Hexobendine, a drug with similar chemical structure

References

1. Deguchi H, Takeya H, Wada H, Gabazza EC, Hayashi N, Urano H, Suzuki K (September 1997). "Dilazep, an antiplatelet agent, inhibits tissue factor expression in endothelial cells and monocytes". Blood. 90 (6): 2345–56. doi:10.1182/blood.V90.6.2345. PMID 9310485.
2. "Pharmaceuticals". Kowa Company Ltd.