Dorema aucheri

Dorema aucheri
Scientific classification
Kingdom:	Plantae
(unranked):	Angiosperms
(unranked):	Eudicots
(unranked):	Asterids
Order:	Apiales
Family:	Apiaceae
Genus:	Dorema
Species:	D. aucheri
Binomial name
	Dorema aucheri; Boiss.

Dorema aucheri is a plant that grows in Iran. In Persian it is called بیلهر (Bilhar). It is the first umbelliferous plant found to produce exudate flavonoids.[1]

It grows in the mountains of western of Iran (Sedeh and Kermanshah). In Persian it is called كندل كوهي (kandale kohi) and in Kermanshah it's known as زو (zo).

Harvested traditionally for cooking, the young leaves and branches of Dorema aucheri are typically used to make a famous pickle known as "Bilhar pickle" or used as vegetables in soup.[2] It can also be cooked by steaming and served with butter as a meal.

Dorema aucheri is used in parts of Iran as traditional medicine, believed to have uses as a stimulant, nervonic, antispasmodic, bronchodilator, expectorant, kidney stone repellent, emmenagogue and analgesic for visceral pain.[3]

Excessive harvesting of these plants for both cooking and traditional medicine has led it to become endangered in local provinces.[2]

Despite being used in both cooking and traditional Iranian medicine, Dorema aucheri has been shown to have hepatotoxic effects when extract of the plant has been injected into albino mice, causing necrosis, inflammation of the liver tissue, cell proliferation, cholestasis, and increases in release of the liver enzymes ALP, ALT (SGPT) and AST (SGOT).[4]

Sources

http://tubiblio.ulb.tu-darmstadt.de/2914/
Mosaddegh, Mahmoud (February 2012). "Ethnobotanical survey of herbal remedies traditionally used in Kohghiluyeh va Boyer Ahmad province of Iran". Journal of Ethnopharmacology. 141: 80–95. doi:10.1016/j.jep.2012.02.004.
Khanahmadi, M; Miraghaee, S Sh; Karimi, I (2017-04-19). "Evaluation of the Antioxidant and antimicrobial Properties of Dorema aucheri plant". Iranian Red Crescent Medical Journal. 14 (10): 684–685. ISSN 2074-1804. PMC 3518988. PMID 23285423.
Mostafavi, Seyed Hossein; Fazilati, Mohammad; Mostafavi, Seyed-Ali; Vahhabi, Mohamma Reza; Mostafavi, Fatemeh; Omidvarinia, Shabnam; Zandi-Atashbar, Navid; Derakhshanian, Hoda; Hajipoor, Abdol Reza (2013-09-01). "Hepatotoxicity of Dorema aucheri (Bilhar) in albino mice" (PDF). Archives of Iranian Medicine. 16 (9): 530–532. ISSN 1735-3947. PMID 23981157.

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[1] ttp://tubiblio.ulb.tu-darmstadt.de/2914/

[:0-2] Mosaddegh, Mahmoud (February 2012). "Ethnobotanical survey of herbal remedies traditionally used in Kohghiluyeh va Boyer Ahmad province of Iran". Journal of Ethnopharmacology. 141: 80–95. doi:10.1016/j.jep.2012.02.004.

[3] Khanahmadi, M; Miraghaee, S Sh; Karimi, I (2017-04-19). "Evaluation of the Antioxidant and antimicrobial Properties of Dorema aucheri plant". Iranian Red Crescent Medical Journal. 14 (10): 684–685. ISSN 2074-1804. PMC 3518988. PMID 23285423.

[4] Mostafavi, Seyed Hossein; Fazilati, Mohammad; Mostafavi, Seyed-Ali; Vahhabi, Mohamma Reza; Mostafavi, Fatemeh; Omidvarinia, Shabnam; Zandi-Atashbar, Navid; Derakhshanian, Hoda; Hajipoor, Abdol Reza (2013-09-01). "Hepatotoxicity of Dorema aucheri (Bilhar) in albino mice" (PDF). Archives of Iranian Medicine. 16 (9): 530–532. ISSN 1735-3947. PMID 23981157.