Influenza A virus subtype H10N8

The influenza A virus subtype H10N8 is an avian influenza virus. It is one of three H10 subtype avian influenza viruses isolated from domestic ducks in China, designated as SH602/H10N8, FJ1761/H10N3 and SX3180/H10N7.[1]

Influenza A virus subtype H10N8
Virus classification
(unranked): Virus
Realm: Riboviria
Kingdom: Orthornavirae
Phylum: Negarnaviricota
Class: Insthoviricetes
Order: Articulavirales
Family: Orthomyxoviridae
Genus: Alphainfluenzavirus
Species: Influenza A virus
Serotype: Influenza A virus subtype H10N8

Presence in non-human species

The first A/H10N8 virus was isolated from a duck in Guangdong province, China, in 2012.[2] The virus shows high pathogenicity in mice. It was also found in waterfowls, feral dogs, and live poultry markets. While multiple H10 genotype viruses (e.g. H10N8, H10N3, and H10N7) are circulating in live poultry markets in China, their potential to infect mammals remains largely unknown.[1]

Presence in humans

Genome sequencing and virus characterization suggest that the virus strains that infected humans originated from poultry markets.[3] H10N8, as well as H10N7, and H6N8, have been detected in people to a lesser extent than other strains.[4]

References
  1. Zhang, Miaomiao; Zhang, Xingxing; Xu, Kaidi; Teng, Qiaoyang; Liu, Qinfang; Li, Xuesong; Yang, Jianmei; Xu, Jianqing; Chen, Hongjun; Zhang, Xiaoyan; Li, Zejun (2016). "Characterization of the Pathogenesis of H10N3, H10N7, and H10N8 Subtype Avian Influenza Viruses Circulating in Ducks". Scientific Reports. 6: 34489. Bibcode:2016NatSR...634489Z. doi:10.1038/srep34489. PMC 5039634. PMID 27678170.
  2. Montomoli, Emanuele; Trombetta, Claudia Maria (2014). "Is influenza A/H10N8 a potential candidate for the next pandemic?". Pathogens and Global Health. 108 (5): 213. doi:10.1179/2047772414Z.000000000215. PMC 4153820. PMID 25175872.
  3. Zhang, Tao; Bi, Yuhai; Tian, Huaiyu; Li, Xiaowen; Liu, Di; Wu, Ying; Jin, Tao; Wang, Yong; Chen, Quanjiao; Chen, Ze; Chang, Jianyu; Gao, George F.; Xu, Bing (2014). "Human Infection with Influenza Virus A(H10N8) from Live Poultry Markets, China, 2014". Emerging Infectious Diseases. 20 (12). doi:10.3201/eid2012.140911. PMID 25425075.
  4. "Influenza Type A Viruses". cdc.gov. Retrieved 20 April 2020.
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