Jean-Paul Vincent

Jean-Paul Vincent FMedSci FRS is a developmental biologist working at the Francis Crick Institute.[3]

Jean-Paul Vincent
Alma mater
Awards
Scientific career
Fields
Institutions
Websitejpvincentlab.com

Research

Vincent has conducted work on the Wnt signalling pathways that help to regulate cell-to-cell interactions.

His work on cell signalling and behaviour has led to an improved understanding of diseases such as cancer in which fundamental biological processes are altered. Earlier in his career, he pioneered the use of caged dye technology to trace the cellular development of fruit fly embryos, and established a relationship between the alignment of frog embryos and their so-called subcortical rotation in the egg.[3]

Awards and honours

Vincent was elected a Fellow of the Royal Society (FRS) in 2013. His certificate of election reads:

JP Vincent has used his training in mathematics, physics to devise new techniques to solve important problems in developmental biology. Using novel laser-staining methods he discovered the cortical rotation in frog eggs. He then co-invented caged dye technology, adapted it to lineage tracing and showed that, in living Drosophila embryos, cells acquire identity step by step. Later, he introduced an HRP fusion strategy to study trafficking and epithelial organisation in transgenic animals. This allowed him show that endocytic trafficking of Wnts is spatially and temporally regulated. His work has spurred many others to investigate how trafficking modulate signalling pathways[4]

He is a Fellow of the Academy of Medical Sciences.[3]

References
  1. Vincent, Jean-Paul (2007). "Jean-Paul Vincent". Current Biology. 17 (2): R41–R42. doi:10.1016/j.cub.2006.12.010. ISSN 0960-9822.
  2. "Jean-Paul Vincent: Biography". Retrieved 2016-03-19.
  3. "Jean-Paul Vincent". London: Royal Society. One or more of the preceding sentences may incorporate text from the royalsociety.org website where "all text published under the heading 'Biography' on Fellow profile pages is available under Creative Commons Attribution 4.0 International License." "Royal Society Terms, conditions and policies". Archived from the original on February 20, 2016. Retrieved 2016-03-09.CS1 maint: bot: original URL status unknown (link)
  4. "EC/2013/39: Vincent, Jean-Paul". The Royal Society. Retrieved 19 March 2016.


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