Liarozole

Liarozole is a retinoic acid metabolism-blocking drug and aromatase inhibitor.[1]

Liarozole

Names
IUPAC name 6-[(3-Chlorophenyl)-imidazol-1-ylmethyl]-1H-benzimidazole
Identifiers
CAS Number	115575-11-6
3D model (JSmol)	Interactive image
ChemSpider	54664
IUPHAR/BPS	5210
PubChem CID	60652
UNII	K0Q29TGV9Y
CompTox Dashboard (EPA)	DTXSID9048277
InChI InChI=1S/C17H13ClN4/c18-14-3-1-2-12(8-14)17(22-7-6-19-11-22)13-4-5-15-16(9-13)21-10-20-15/h1-11,17H,(H,20,21) Key: UGFHIPBXIWJXNA-UHFFFAOYSA-N InChI=1/C17H13ClN4/c18-14-3-1-2-12(8-14)17(22-7-6-19-11-22)13-4-5-15-16(9-13)21-10-20-15/h1-11,17H,(H,20,21) Key: UGFHIPBXIWJXNA-UHFFFAOYAV
SMILES C1=CC(=CC(=C1)Cl)C(C2=CC3=C(C=C2)N=CN3)N4C=CN=C4
Properties
Chemical formula	C17H13ClN4
Molar mass	308.77 g·mol^−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

References

1. Vahlquist, A; Blockhuys, S; Steijlen, P; Van Rossem, K; Didona, B; Blanco, D; Traupe, H (2013). "Oral liarozole in the treatment of patients with moderate/severe lamellar ichthyosis: Results of a randomized, double-blind, multinational, placebo-controlled phase II/III trial". The British Journal of Dermatology. 170 (1): 173–81. doi:10.1111/bjd.12626. PMC 4232915. PMID 24102348.