Mannosylglucosyl-3-phosphoglycerate synthase

Mannosylglucosyl-3-phosphoglycerate synthase (EC 2.4.1.270, MggA) is an enzyme with systematic name GDP-mannose:2-O-(alpha-D-glucosyl)-3-phospho-D-glycerate 2-O-alpha-D-mannosyltransferase.[1] This enzyme catalyses the following chemical reaction

GDP-mannose + 2-O-(alpha-D-glucopyranosyl)-3-phospho-D-glycerate GDP + 2-O-[2-O-(alpha-D-mannopyranosyl)-alpha-D-glucopyranosyl]-3-phospho-D-glycerate
Mannosylglucosyl-3-phosphoglycerate synthase
Identifiers
EC number2.4.1.270
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

The enzyme is involved in synthesis of 2-[2-O-(alpha-D-mannopranosyl)-alpha-D-glucopyranosyl]-D-glycerate.

References

  1. Fernandes C, Mendes V, Costa J, Empadinhas N, Jorge C, Lamosa P, Santos H, da Costa MS (March 2010). "Two alternative pathways for the synthesis of the rare compatible solute mannosylglucosylglycerate in Petrotoga mobilis". Journal of Bacteriology. 192 (6): 1624–33. doi:10.1128/JB.01424-09. PMC 2832527. PMID 20061481.
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