PIP4K2C

Phosphatidylinositol-5-phosphate 4-kinase, type II, gamma is an enzyme in humans that is encoded by the PIP4K2C gene.[5] It is one of the phosphatidylinositol 4-phosphate 5-kinases.

PIP4K2C
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2GK9
Identifiers
Aliases	PIP4K2C, PIP5K2C, phosphatidylinositol-5-phosphate 4-kinase type 2 gamma
External IDs	OMIM: 617104 MGI: 2152214 HomoloGene: 23484 GeneCards: PIP4K2C
Gene location (Human) Chr. Chromosome 12 (human)[1] Band 12q13.3 Start 57,591,174 bp[1] End 57,603,418 bp[1]
Gene location (Mouse) Chr. Chromosome 10 (mouse)[2] Band 10|10 D3 Start 127,197,067 bp[2] End 127,211,585 bp[2]
Gene ontology Molecular function • transferase activity • nucleotide binding • kinase activity • phosphatidylinositol phosphate kinase activity • identical protein binding • ATP binding • 1-phosphatidylinositol-5-phosphate 4-kinase activity Cellular component • cytoplasm • cytosol • membrane • autophagosome • extracellular exosome Biological process • phosphatidylinositol metabolic process • positive regulation of autophagosome assembly • phosphorylation • phosphatidylinositol phosphorylation • regulation of autophagy • phosphatidylinositol biosynthetic process • regulation of phosphatidylinositol 3-kinase signaling Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	79837	117150
Ensembl	ENSG00000166908	ENSMUSG00000025417
UniProt	Q8TBX8	Q91XU3
RefSeq (mRNA)	NM_001146258 NM_001146259 NM_001146260 NM_024779	NM_054097 NM_001359280
RefSeq (protein)	NP_001139730 NP_001139731 NP_001139732 NP_079055	NP_473438 NP_001346209
Location (UCSC)	Chr 12: 57.59 – 57.6 Mb	Chr 10: 127.2 – 127.21 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000166908 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000025417 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: Phosphatidylinositol-5-phosphate 4-kinase, type II, gamma".

External links

• PDBe-KB provides an overview of all the structure information available in the PDB for Human Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma (PIP4K2C)