RRP9

U3 small nucleolar RNA-interacting protein 2 is a protein that in humans is encoded by the RRP9 gene.[5][6][7]

RRP9
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4J0W, 4JXM
Identifiers
Aliases	RRP9, RNU3IP2, U3-55K, ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast), ribosomal RNA processing 9, U3 small nucleolar RNA binding protein
External IDs	MGI: 2384313 HomoloGene: 3452 GeneCards: RRP9
Gene location (Human) Chr. Chromosome 3 (human)[1] Band 3p21.2 Start 51,933,429 bp[1] End 51,941,904 bp[1]
Gene location (Mouse) Chr. Chromosome 9 (mouse)[2] Band 9 F1|9 57.59 cM Start 106,475,963 bp[2] End 106,485,424 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • U3 snoRNA binding • RNA binding • snoRNA binding Cellular component • small-subunit processome • nucleolus • box C/D snoRNP complex • nucleoplasm • cell nucleus Biological process • rRNA processing Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	9136	27966
Ensembl	ENSG00000114767	ENSMUSG00000041506
UniProt	O43818	Q91WM3
RefSeq (mRNA)	NM_004704	NM_145620
RefSeq (protein)	NP_004695	NP_663595
Location (UCSC)	Chr 3: 51.93 – 51.94 Mb	Chr 9: 106.48 – 106.49 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

See also

• Fibrillarin
• Small nucleolar RNA U3
• RCL1
• RRP9
• UTP6
• UTP11L
• UTP14A
• UTP15

References

1. GRCh38: Ensembl release 89: ENSG00000114767 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000041506 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Pluk H, Soffner J, Luhrmann R, van Venrooij WJ (Jan 1998). "cDNA Cloning and Characterization of the Human U3 Small Nucleolar Ribonucleoprotein Complex-Associated 55-Kilodalton Protein". Mol Cell Biol. 18 (1): 488–98. doi:10.1128/mcb.18.1.488. PMC 121518. PMID 9418896.
6. Verheggen C, Lafontaine DL, Samarsky D, Mouaikel J, Blanchard JM, Bordonne R, Bertrand E (May 2002). "Mammalian and yeast U3 snoRNPs are matured in specific and related nuclear compartments". EMBO J. 21 (11): 2736–45. doi:10.1093/emboj/21.11.2736. PMC 126019. PMID 12032086.
7. "Entrez Gene: RRP9 RRP9, small subunit (SSU) processome component, homolog (yeast)".

Further reading

• Lukowiak AA, Granneman S, Mattox SA, et al. (2000). "Interaction of the U3-55k protein with U3 snoRNA is mediated by the Box B/C motif of U3 and the WD repeats of U3-55k". Nucleic Acids Res. 28 (18): 3462–71. doi:10.1093/nar/28.18.3462. PMC 110750. PMID 10982864.
• Andersen JS, Lyon CE, Fox AH, et al. (2002). "Directed proteomic analysis of the human nucleolus". Curr. Biol. 12 (1): 1–11. doi:10.1016/S0960-9822(01)00650-9. PMID 11790298. S2CID 14132033.
• Granneman S, Pruijn GJ, Horstman W, et al. (2003). "The hU3-55K protein requires 15.5K binding to the box B/C motif as well as flanking RNA elements for its association with the U3 small nucleolar RNA in Vitro". J. Biol. Chem. 277 (50): 48490–500. doi:10.1074/jbc.M206631200. PMID 12381732.
• Scherl A, Couté Y, Déon C, et al. (2003). "Functional Proteomic Analysis of Human Nucleolus". Mol. Biol. Cell. 13 (11): 4100–9. doi:10.1091/mbc.E02-05-0271. PMC 133617. PMID 12429849.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Watkins NJ, Lemm I, Ingelfinger D, et al. (2005). "Assembly and maturation of the U3 snoRNP in the nucleoplasm in a large dynamic multiprotein complex". Mol. Cell. 16 (5): 789–98. doi:10.1016/j.molcel.2004.11.012. hdl:11858/00-001M-0000-0012-EB89-8. PMID 15574333.
• Andersen JS, Lam YW, Leung AK, et al. (2005). "Nucleolar proteome dynamics". Nature. 433 (7021): 77–83. doi:10.1038/nature03207. PMID 15635413. S2CID 4344740.
• Barrios-Rodiles M, Brown KR, Ozdamar B, et al. (2005). "High-throughput mapping of a dynamic signaling network in mammalian cells". Science. 307 (5715): 1621–5. doi:10.1126/science.1105776. PMID 15761153. S2CID 39457788.
• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.

External links

• PDBe-KB provides an overview of all the structure information available in the PDB for Human U3 small nucleolar RNA-interacting protein 2 (RRP9)