Ribonuclease T2
Ribonuclease T2 (EC 3.1.27.1, ribonuclease II, base-non-specific ribonuclease, nonbase-specific RNase, RNase (non-base specific), non-base specific ribonuclease, nonspecific RNase, RNase Ms, RNase M, RNase II, Escherichia coli ribonuclease II, ribonucleate nucleotido-2'-transferase (cyclizing), acid ribonuclease, RNAase CL, Escherichia coli ribonuclease I' ribonuclease PP2, ribonuclease N2, ribonuclease M, acid RNase, ribonnuclease (non-base specific), ribonuclease (non-base specific), RNase T2, ribonuclease PP3, ribonucleate 3'-oligonucleotide hydrolase, ribonuclease U4) is an enzyme.[1][2][3][4] It is a type of endoribonuclease. This enzyme catalyses the following chemical reaction
- Two-stage endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides with 2',3'-cyclic phosphate intermediates
| Ribonuclease T2 | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 3.1.27.1 | ||||||||
| CAS number | 37278-25-4 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
See also
References
- García-Segura JM, Orozco MM, Fominaya JM, Gavilanes JG (July 1986). "Purification, molecular and enzymic characterization of an acid RNase from the insect Ceratitis capitata". European Journal of Biochemistry. 158 (2): 367–72. doi:10.1111/j.1432-1033.1986.tb09760.x. PMID 3732273.
- Heppel LA, Davies DR (1966). "Pig liver nuclei ribonuclease". In Cantoni GL (ed.). Procedures in Nucleic Acid Research. New York: Procedures in Nucleic Acid Research. pp. 31–36.
- Reddi KK, Mauser LJ (March 1965). "Studies on the formation of tobacco mosaic virus ribonucleic acid. VI. Mode of degradation of host ribonucleic acid to ribonucleosides and their conversion to ribonucleoside 5′-phosphates". Proceedings of the National Academy of Sciences of the United States of America. 53 (3): 607–13. doi:10.1073/pnas.53.3.607. PMC 336984. PMID 14338240.
- Uchida T, Egami F (January 1967). "The specificity of ribonuclease T2". Journal of Biochemistry. 61 (1): 44–53. PMID 6048969.
External links
- Ribonuclease+T2 at the US National Library of Medicine Medical Subject Headings (MeSH)
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