SSBP3

Single-stranded DNA-binding protein 3 is a protein that in humans is encoded by the SSBP3 gene.[5][6]

SSBP3
Identifiers
Aliases	SSBP3, CSDP, SSDP, SSDP1, single stranded DNA binding protein 3
External IDs	OMIM: 607390 MGI: 1919725 HomoloGene: 23411 GeneCards: SSBP3
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1p32.3 Start 54,225,432 bp[1] End 54,413,479 bp[1]
Gene location (Mouse) Chr. Chromosome 4 (mouse)[2] Band 4|4 C7 Start 106,910,701 bp[2] End 107,049,694 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • single-stranded DNA binding • DNA binding • GO:0001948 protein binding • GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding • GO:0001077, GO:0001212, GO:0001213, GO:0001211, GO:0001205 DNA-binding transcription activator activity, RNA polymerase II-specific Cellular component • cell nucleus • macromolecular complex Biological process • midbrain-hindbrain boundary initiation • positive regulation of transcription, DNA-templated • prechordal plate formation • head morphogenesis • positive regulation of anterior head development • regulation of transcription, DNA-templated • hematopoietic progenitor cell differentiation • transcription, DNA-templated • positive regulation of cell proliferation • transcription from RNA polymerase II promoter • positive regulation of transcription from RNA polymerase II promoter • head development • macromolecular complex assembly Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	23648	72475
Ensembl	ENSG00000157216	ENSMUSG00000061887
UniProt	Q9BWW4	Q9D032
RefSeq (mRNA)	NM_001009955 NM_018070 NM_145716	NM_023672 NM_198438 NM_001355532
RefSeq (protein)	NP_001009955 NP_060540 NP_663768	NP_076161 NP_940840 NP_001342461
Location (UCSC)	Chr 1: 54.23 – 54.41 Mb	Chr 4: 106.91 – 107.05 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000157216 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000061887 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Castro P, Liang H, Liang JC, Nagarajan L (July 2002). "A novel, evolutionarily conserved gene family with putative sequence-specific single-stranded DNA-binding activity". Genomics. 80 (1): 78–85. doi:10.1006/geno.2002.6805. PMID 12079286.
6. "Entrez Gene: SSBP3 single stranded DNA binding protein 3".

Further reading

• Wu L (January 2006). "Structure and functional characterization of single-strand DNA binding protein SSDP1: carboxyl-terminal of SSDP1 has transcription activity". Biochemical and Biophysical Research Communications. 339 (3): 977–84. doi:10.1016/j.bbrc.2005.11.098. PMID 16325762.
• Chen L, Segal D, Hukriede NA, Podtelejnikov AV, Bayarsaihan D, Kennison JA, Ogryzko VV, Dawid IB, Westphal H (October 2002). "Ssdp proteins interact with the LIM-domain-binding protein Ldb1 to regulate development". Proceedings of the National Academy of Sciences of the United States of America. 99 (22): 14320–5. Bibcode:2002PNAS...9914320C. doi:10.1073/pnas.212532399. PMC 137882. PMID 12381786.
• Raval-Fernandes S, Kickhoefer VA, Rome LH (September 1999). "Cloning of a cDNA encoding a sequence-specific single-stranded-DNA-binding protein from Rattus norvegicus". Gene. 237 (1): 201–7. doi:10.1016/S0378-1119(99)00289-9. PMID 10524251.
• Adams MD, Kerlavage AR, Fleischmann RD, Fuldner RA, Bult CJ, Lee NH, Kirkness EF, Weinstock KG, Gocayne JD, White O (September 1995). "Initial assessment of human gene diversity and expression patterns based upon 83 million nucleotides of cDNA sequence". Nature. 377 (6547 Suppl): 3–174. PMID 7566098.