Stratified columnar epithelium

Stratified columnar epithelium
Details
Shape	Many layers of flat cells
Identifiers
TH	H2.00.02.0.02032
FMA	45564
	Anatomical terms of microanatomy;

Stratified columnar epithelium is a rare type of epithelial tissue composed of column-shaped cells arranged in multiple layers. It is found in the conjunctiva, pharynx, anus, and male urethra.

Location

Stratified columnar epithelia are found in a variety of locations, including:

parts of the conjunctiva of the eye[1][2]
parts of the pharynx[3]
anus[3][4]
uterus
male urethra and vas deferens[3][5]
lobar ducts in the salivary glands

Embryology

Stratified columnar epithelium is initially present in parts of the gastrointestinal tract in utero, before being replaced with other types of epithelium. For example, by 8 weeks, it covers the lining of the stomach.[6][7] By 17 weeks, it is replaced by simple columnar epithelium.[6] This is also found in the fetal esophagus.[7]

Function

The cells function in secretion and protection.

References

Soni, Vandana; Pandey, Vikas; Tiwari, Rahul; Asati, Saket; Tekade, Rakesh K. (2019-01-01), Tekade, Rakesh K. (ed.), "Chapter 13 - Design and Evaluation of Ophthalmic Delivery Formulations", Basic Fundamentals of Drug Delivery, Advances in Pharmaceutical Product Development and Research, Academic Press, pp. 473–538, doi:10.1016/b978-0-12-817909-3.00013-3, ISBN 978-0-12-817909-3, retrieved 2020-11-29
Forrester, John V.; Dick, Andrew D.; McMenamin, Paul G.; Roberts, Fiona; Pearlman, Eric (2016-01-01), Forrester, John V.; Dick, Andrew D.; McMenamin, Paul G.; Roberts, Fiona (eds.), "Chapter 1 - Anatomy of the eye and orbit", The Eye (Fourth Edition), W.B. Saunders, pp. 1–102.e2, doi:10.1016/b978-0-7020-5554-6.00001-0, ISBN 978-0-7020-5554-6, retrieved 2020-11-29
Cadwell, K.; Marchiando, A. M. (2016-01-01), "Function of Epithelial Barriers", in Bradshaw, Ralph A.; Stahl, Philip D. (eds.), Encyclopedia of Cell Biology, Waltham: Academic Press, pp. 687–694, doi:10.1016/b978-0-12-394447-4.30104-3, ISBN 978-0-12-394796-3, retrieved 2020-11-29
Gordon, Philip H. (2005-01-01), Fazio, Victor W.; Church, James M.; Delaney, Conor P. (eds.), "Anatomy and Physiology of the Anorectum", Current Therapy in Colon and Rectal Surgery (Second Edition), Philadelphia: Mosby, pp. 1–9, doi:10.1016/b978-1-55664-480-1.50006-x, ISBN 978-1-55664-480-1, retrieved 2020-11-29
Johnson, L.; Welsh, T. H.; Curley, K. O.; Johnston, C. E. (2010-01-01), McQueen, Charlene A. (ed.), "11.02 - Anatomy and Physiology of the Male Reproductive System and Potential Targets of Toxicants", Comprehensive Toxicology (Second Edition), Oxford: Elsevier, pp. 5–59, doi:10.1016/b978-0-08-046884-6.01102-7, ISBN 978-0-08-046884-6, retrieved 2020-11-29
Chandrasoma, Parakrama T.; DeMeester, Tom R. (2006-01-01), Chandrasoma, Parakrama T.; DeMeester, Tom R. (eds.), "CHAPTER 3 - Fetal Development of the Esophagus and Stomach", GERD, Burlington: Academic Press, pp. 41–63, doi:10.1016/b978-012369416-4/50003-0, ISBN 978-0-12-369416-4, retrieved 2020-11-29
Chandrasoma, Parakrama T. (2018), "Molecular Evolution of Esophageal Epithelial Metaplasia", GERD, Elsevier, pp. 457–478, doi:10.1016/b978-0-12-809855-4.00015-4, ISBN 978-0-12-809855-4, retrieved 2020-11-29

External links

Anatomy Atlases - Microscopic Anatomy, plate 02.23 – "Stratified Columnar Epithelium"

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[1] Soni, Vandana; Pandey, Vikas; Tiwari, Rahul; Asati, Saket; Tekade, Rakesh K. (2019-01-01), Tekade, Rakesh K. (ed.), "Chapter 13 - Design and Evaluation of Ophthalmic Delivery Formulations", Basic Fundamentals of Drug Delivery, Advances in Pharmaceutical Product Development and Research, Academic Press, pp. 473–538, doi:10.1016/b978-0-12-817909-3.00013-3, ISBN 978-0-12-817909-3, retrieved 2020-11-29

[2] Forrester, John V.; Dick, Andrew D.; McMenamin, Paul G.; Roberts, Fiona; Pearlman, Eric (2016-01-01), Forrester, John V.; Dick, Andrew D.; McMenamin, Paul G.; Roberts, Fiona (eds.), "Chapter 1 - Anatomy of the eye and orbit", The Eye (Fourth Edition), W.B. Saunders, pp. 1–102.e2, doi:10.1016/b978-0-7020-5554-6.00001-0, ISBN 978-0-7020-5554-6, retrieved 2020-11-29

[:0-3] Cadwell, K.; Marchiando, A. M. (2016-01-01), "Function of Epithelial Barriers", in Bradshaw, Ralph A.; Stahl, Philip D. (eds.), Encyclopedia of Cell Biology, Waltham: Academic Press, pp. 687–694, doi:10.1016/b978-0-12-394447-4.30104-3, ISBN 978-0-12-394796-3, retrieved 2020-11-29

[4] Gordon, Philip H. (2005-01-01), Fazio, Victor W.; Church, James M.; Delaney, Conor P. (eds.), "Anatomy and Physiology of the Anorectum", Current Therapy in Colon and Rectal Surgery (Second Edition), Philadelphia: Mosby, pp. 1–9, doi:10.1016/b978-1-55664-480-1.50006-x, ISBN 978-1-55664-480-1, retrieved 2020-11-29

[5] Johnson, L.; Welsh, T. H.; Curley, K. O.; Johnston, C. E. (2010-01-01), McQueen, Charlene A. (ed.), "11.02 - Anatomy and Physiology of the Male Reproductive System and Potential Targets of Toxicants", Comprehensive Toxicology (Second Edition), Oxford: Elsevier, pp. 5–59, doi:10.1016/b978-0-08-046884-6.01102-7, ISBN 978-0-08-046884-6, retrieved 2020-11-29

[:1-6] Chandrasoma, Parakrama T.; DeMeester, Tom R. (2006-01-01), Chandrasoma, Parakrama T.; DeMeester, Tom R. (eds.), "CHAPTER 3 - Fetal Development of the Esophagus and Stomach", GERD, Burlington: Academic Press, pp. 41–63, doi:10.1016/b978-012369416-4/50003-0, ISBN 978-0-12-369416-4, retrieved 2020-11-29

[:2-7] Chandrasoma, Parakrama T. (2018), "Molecular Evolution of Esophageal Epithelial Metaplasia", GERD, Elsevier, pp. 457–478, doi:10.1016/b978-0-12-809855-4.00015-4, ISBN 978-0-12-809855-4, retrieved 2020-11-29