TAF1D

TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa is a protein that in humans is encoded by the TAF1D gene.[5]

TAF1D
Identifiers
Aliases	TAF1D, JOSD3, RAFI41, TAF(I)41, TAFI41, TATA-box binding protein associated factor, RNA polymerase I subunit D
External IDs	OMIM: 612823 MGI: 1922566 HomoloGene: 11472 GeneCards: TAF1D
Gene location (Human) Chr. Chromosome 11 (human)[1] Band 11q21 Start 93,729,948 bp[1] End 93,784,391 bp[1]
Gene location (Mouse) Chr. Chromosome 9 (mouse)[2] Band 9|9 A2 Start 15,306,214 bp[2] End 15,316,991 bp[2]
Gene ontology Molecular function • DNA binding • GO:0001948 protein binding Cellular component • RNA polymerase transcription factor SL1 complex • cell nucleus • nucleoplasm • microtubule organizing center Biological process • transcription initiation from RNA polymerase I promoter • termination of RNA polymerase I transcription • positive regulation of gene expression, epigenetic • regulation of transcription, DNA-templated • transcription, DNA-templated • transcription elongation from RNA polymerase I promoter Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	79101	75316
Ensembl	ENSG00000166012	ENSMUSG00000031939
UniProt	Q9H5J8	Q9D4V4
RefSeq (mRNA)	NM_024116	NM_026541 NM_027261 NM_029248
RefSeq (protein)	NP_077021	NP_081537 NP_083524
Location (UCSC)	Chr 11: 93.73 – 93.78 Mb	Chr 9: 15.31 – 15.32 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

Function

TAF1D is a member of the SL1 complex, which includes TBP and TAF1A, TAF1B, and TAF1C, and plays a role in RNA polymerase I transcription.[6][7]

References

1. GRCh38: Ensembl release 89: ENSG00000166012 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000031939 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa".
6. Wang L, Bhattacharyya N, Chelsea DM, Escobar PF, Banerjee S (November 2004). "A novel nuclear protein, MGC5306 interacts with DNA polymerase beta and has a potential role in cellular phenotype". Cancer Research. 64 (21): 7673–7. doi:10.1158/0008-5472.CAN-04-2801. PMID 15520167.
7. Gorski JJ, Pathak S, Panov K, Kasciukovic T, Panova T, Russell J, Zomerdijk JC (March 2007). "A novel TBP-associated factor of SL1 functions in RNA polymerase I transcription". The EMBO Journal. 26 (6): 1560–8. doi:10.1038/sj.emboj.7601601. PMC 1829371. PMID 17318177.