Tombusvirus

Tombusvirus is a genus of viruses, in the family Tombusviridae. Plants serve as natural hosts. There are currently 17 species in this genus including the type species Tomato bushy stunt virus. Symptoms associated with this genus include mosaic.[1][2] The name of the genus comes from the type species: Tomato bushy stunt virus.

Tombusvirus
Virus classification
(unranked): Virus
Realm: Riboviria
Kingdom: Orthornavirae
Phylum: Kitrinoviricota
Class: Tolucaviricetes
Order: Tolivirales
Family: Tombusviridae
Subfamily: Procedovirinae
Genus: Tombusvirus
Type species
*Tomato bushy stunt virus

Taxonomy

Group: ssRNA(+)

[2]

Structure

Viruses in Tombusvirus are non-enveloped, with icosahedral and Spherical geometries, and T=3 symmetry. The diameter is around 28-34 nm. Genomes are linear and non-segmented, positive sense, single-stranded RNA, around 4-5.4kb in length.[1] These virions have a regular surface structure and are composed of 17% nucleic acid.

GenusStructureSymmetryCapsidGenomic arrangementGenomic segmentation
TombusvirusIcosahedralT=3Non-envelopedLinearMonopartite

Life cycle

Viral replication is cytoplasmic, and is lysogenic. Entry into the host cell is achieved by penetration into the host cell. Replication follows the positive stranded RNA virus replication model. Positive stranded rna virus transcription, using the premature termination model of subgenomic RNA transcription is the method of transcription. Translation takes place by suppression of termination. The virus exits the host cell by tubule-guided viral movement. Plants serve as the natural host. Transmission routes are mechanical, seed borne, and contact.[1]

GenusHost detailsTissue tropismEntry detailsRelease detailsReplication siteAssembly siteTransmission
TombusvirusPlantsNoneViral movement; mechanical inoculationViral movementCytoplasmCytoplasmMechanical: contact; seed

The virus uses the cis-regulatory elements, Tombus virus defective interfering (DI) RNA region 3 and Tombusvirus 5' UTR to control expression of defective interfering RNAs and viral RNA replication.[3][4]

References
  1. "Viral Zone". ExPASy. Retrieved 15 June 2015.
  2. ICTV. "Virus Taxonomy: 2014 Release". Retrieved 15 June 2015.
  3. Ray D, White KA (2003). "An internally located RNA hairpin enhances replication of Tomato bushy stunt virus RNAs". J. Virol. 77 (1): 245–57. doi:10.1128/JVI.77.1.245-257.2003. PMC 140596. PMID 12477830.
  4. Wu B, Vanti WB, White KA (2001). "An RNA domain within the 5' untranslated region of the tomato bushy stunt virus genome modulates viral RNA replication". J. Mol. Biol. 305 (4): 741–56. doi:10.1006/jmbi.2000.4298. PMID 11162089.
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