Anne Ridley

Education

Ridley was educated at Clare College, Cambridge[1] and awarded a Bachelor of Arts degree in Natural Sciences (Biochemistry) from the University of Cambridge in 1985. After being encouraged by Tim Hunt to pursue a career in research[5] she moved to the University of London where she was awarded a Doctor of Philosophy degree in 1989[10] for research investigating the regulation of oncogenes in Schwann cells supervised by Hartmut Land[5][11][12] at the Imperial Cancer Research Fund.

Career and research

Ridley started her career as a postdoctoral researcher at the Whitehead Institute in Cambridge, Massachusetts from 1989 to 1990 and the Institute of Cancer Research in London from 1990 to 1993. She was appointed research group leader at the Ludwig Institute for Cancer Research at University College London (UCL) from 1993 to 2007 and Professor of Cell Biology at UCL from 2003 to 2007.

Since 2007, she has been Professor at King's College London[7] and her research has made contributions to our understanding of cancer, tumour progression and inflammation through her work on cell migration and the Rho family of GTPases.[13][14][15][16]

Work in her laboratory[17][18][19] has influenced many areas of medical science, from metastasis to cardiovascular disease and infection. Funding for her research has been provided by the Biotechnology and Biological Sciences Research Council (BBSRC), the Medical Research Council (MRC),[20] Cancer Research UK (CRUK) and Worldwide Cancer Research.[8][21]

Awards and honours

Ridley was elected a Fellow of the Royal Society (FRS) in 2017.[3] She was also awarded the Robert Hooke Medal by the British Society of Cell Biology (BSCB) in 2000,[3] EMBO Membership in 2002[2] and the Liliane Bettencourt Prize for the Life Sciences in 2004.[3] She was elected a Fellow of the Royal Society of Biology (FRSB) in 2009 and a Fellow of the Academy of Medical Sciences (FMedSci) in 2012.[3] She became an honorary fellow of the Royal Microscopical Society (FRMS) in 2014.[3]

References
  1. Anon (2017). "RIDLEY, Prof. Anne Jacqueline". Who's Who. ukwhoswho.com (online Oxford University Press ed.). A & C Black, an imprint of Bloomsbury Publishing plc. doi:10.1093/ww/9780199540884.013.258560. (subscription or UK public library membership required) (subscription required)
  2. Anon (2002). "EMBO Member: Anne Ridley". people.embo.org. Heidelberg: European Molecular Biology Organization.
  3. Anon (2017). "Professor Anne Ridley FRS". London: royalsociety.org.
  4. Anon (2016). "Meet the Professors: Anne Ridley". King's College London.
  5. Anon (2006). "Anne Ridley Profile" (PDF). ascb.org. Archived from the original (PDF) on 13 July 2007.
  6. Bristol, University of. "July: Anne Ridley - News - University of Bristol". www.bristol.ac.uk.
  7. Anon (2016). "Professor Anne Ridley". London: King's College London. Archived from the original on 27 March 2016.
  8. Anne Ridley publications from Europe PubMed Central
  9. Anne Ridley publications indexed by the Scopus bibliographic database. (subscription required)
  10. Ridley, Anne Jacqueline (1989). Mechanisms of oncogene action and interaction in Schwann cells. london.ac.uk (PhD thesis). University of London. OCLC 940319396.
  11. Ridley, A. J.; Davis, J. B.; Stroobant, P.; Land, H. (1989). "Transforming growth factors-beta 1 and beta 2 are mitogens for rat Schwann cells". Journal of Cell Biology. 109 (6 Pt 2): 3419–3424. doi:10.1083/jcb.109.6.3419. ISSN 0021-9525. PMC 2115905. PMID 2557356.
  12. Ridley, A J; Paterson, H F; Noble, M; Land, H (1988). "Ras-mediated cell cycle arrest is altered by nuclear oncogenes to induce Schwann cell transformation". The EMBO Journal. 7 (6): 1635–1645. doi:10.1002/j.1460-2075.1988.tb02990.x. ISSN 0261-4189. PMC 457147. PMID 3049071.
  13. Ridley, Anne J (2015). "Rho GTPase signalling in cell migration". Current Opinion in Cell Biology. 36: 103–112. doi:10.1016/j.ceb.2015.08.005. PMC 4728192. PMID 26363959.
  14. Ridley, Anne Jacqueline (2016). "Anne Ridley: Networking with Rho GTPases". Trends in Cell Biology. 26 (7): 465–466. doi:10.1016/j.tcb.2016.04.005. ISSN 0962-8924. PMID 27166090. (subscription required)
  15. Heasman, Sarah J.; Ridley, Anne J. (2008). "Mammalian Rho GTPases: new insights into their functions from in vivo studies". Nature Reviews Molecular Cell Biology. 9 (9): 690–701. doi:10.1038/nrm2476. PMID 18719708. S2CID 16205866. (subscription required)
  16. Ridley, Anne J. (2006). "Rho GTPases and actin dynamics in membrane protrusions and vesicle trafficking". Trends in Cell Biology. 16 (10): 522–529. doi:10.1016/j.tcb.2006.08.006. ISSN 0962-8924. PMID 16949823. (subscription required)
  17. Cantelli, Gaia (2016). Transcriptional programs controlling actomyosin contractility in melanoma. ethos.bl.uk (PhD thesis). King's College London. EThOS uk.bl.ethos.700781.
  18. Dwyer, Joseph (2015). Characterisation of the formin protein FHOD1 in striated muscle. ethos.bl.uk (PhD thesis). King's College London. OCLC 929654231. EThOS uk.bl.ethos.677210.
  19. Philippeos, Christina (2014). Insulin signalling in endothelial cells. ethos.bl.uk (PhD thesis). King's College London. OCLC 918458935. EThOS uk.bl.ethos.677057.
  20. "UK government grants awarded to Anne Ridley". rcuk.ac.uk. Swindon: Research Councils UK.
  21. Anne Ridley ORCID 0000-0001-8186-5708
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