Crotylbarbital

Crotylbarbital (Mepertan, Kalipnon, Barotal), also known as crotarbital, is a barbiturate derivative developed by Eli Lilly in the 1930s[1] It has sedative and hypnotic effects,[2] and was used for the treatment of insomnia until it was replaced by newer alternative drugs with less side effects and lower risk of overdose.

Crotylbarbital

Clinical data
ATC code	none
Identifiers
IUPAC name 5-but-2-enyl-5-ethyl-1,3-diazinane-2,4,6-trione
CAS Number	1952-67-6
PubChem CID	5364821
ChemSpider	4516954
UNII	SXW2HL5JU7
CompTox Dashboard (EPA)	DTXSID90905095
ECHA InfoCard	100.016.162
Chemical and physical data
Formula	C10H14N2O3
Molar mass	210.233 g·mol^−1
3D model (JSmol)	Interactive image
SMILES O=C1NC(=O)NC(=O)C1(CC)C/C=C/C
InChI InChI=1S/C10H14N2O3/c1-3-5-6-10(4-2)7(13)11-9(15)12-8(10)14/h3,5H,4,6H2,1-2H3,(H2,11,12,13,14,15)/b5-3+ Key:KNMOHCLEINXVBG-HWKANZROSA-N
(verify)

See also

• Barbiturate

References

1. US 2250422, Shonle HA, Doran WJ, "Alkyl-crotyl barbituric acids and their salts", issued 22 July 1941, assigned to Eli Lilly
2. Walther T, Meyer FP, Puchta K, Walther H (June 1983). "Effect of an acute dose of crotylbarbital on reaction time and attention testing in healthy human subjects". International Journal of Clinical Pharmacology, Therapy, and Toxicology. 21 (6): 306–10. PMID 6136469.