Dimiracetam

Dimiracetam
Names
	IUPAC name (RS)-3,6,7,7a-Tetrahydro-1H-pyrrolo[1,2-a]imidazole-2,5-dione
Identifiers
CAS Number	126100-97-8 ;
3D model (JSmol)	Interactive image; Interactive image;
ChEMBL	ChEMBL337612 ;
ChemSpider	59358 ;
PubChem CID	65955;
UNII	4AW7F70MZO ;
	InChI InChI=1S/C6H8N2O2/c9-5-3-8-4(7-5)1-2-6(8)10/h4H,1-3H2,(H,7,9) Key: XTXXOHPHLNROBN-UHFFFAOYSA-N ; InChI=1/C6H8N2O2/c9-5-3-8-4(7-5)1-2-6(8)10/h4H,1-3H2,(H,7,9) Key: XTXXOHPHLNROBN-UHFFFAOYAX;
	SMILES C1CC(=O)N2C1NC(=O)C2; O=C2NC1N(C(=O)CC1)C2;
Properties
Chemical formula	C6H8N2O2
Molar mass	140.142 g·mol−1
Pharmacology
Legal status	AU: S4 (Prescription only) ;
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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	Infobox references

Dimiracetam is a nootropic drug of the racetam family,[1] derivatives of which may have application in the treatment of neuropathic pain.[2]

Legality

Australia

Dimiracetam is a schedule 4 substance in Australia under the Poisons Standard (February 2020).[3] A schedule 4 substance is classified as "Prescription Only Medicine, or Prescription Animal Remedy – Substances, the use or supply of which should be by or on the order of persons permitted by State or Territory legislation to prescribe and should be available from a pharmacist on prescription." [3]

References

Pinza M, Farina C, Cerri A, Pfeiffer U, Riccaboni MT, Banfi S, et al. (December 1993). "Synthesis and pharmacological activity of a series of dihydro-1H-pyrrolo[1,2-a]imidazole-2,5(3H,6H)-diones, a novel class of potent cognition enhancers". Journal of Medicinal Chemistry. 36 (26): 4214–20. doi:10.1021/jm00078a011. PMID 8277504.
Farina C, Gagliardi S, Ghelardini C, Martinelli M, Norcini M, Parini C, et al. (March 2008). "Synthesis and biological evaluation of novel dimiracetam derivatives useful for the treatment of neuropathic pain". Bioorganic & Medicinal Chemistry. 16 (6): 3224–32. doi:10.1016/j.bmc.2007.12.015. PMID 18171618.
Poisons Standard February 2020. comlaw.gov.au

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[1] Pinza M, Farina C, Cerri A, Pfeiffer U, Riccaboni MT, Banfi S, et al. (December 1993). "Synthesis and pharmacological activity of a series of dihydro-1H-pyrrolo[1,2-a]imidazole-2,5(3H,6H)-diones, a novel class of potent cognition enhancers". Journal of Medicinal Chemistry. 36 (26): 4214–20. doi:10.1021/jm00078a011. PMID 8277504.

[2] Farina C, Gagliardi S, Ghelardini C, Martinelli M, Norcini M, Parini C, et al. (March 2008). "Synthesis and biological evaluation of novel dimiracetam derivatives useful for the treatment of neuropathic pain". Bioorganic & Medicinal Chemistry. 16 (6): 3224–32. doi:10.1016/j.bmc.2007.12.015. PMID 18171618.

[Poisons_Stanrard-3] Poisons Standard February 2020. comlaw.gov.au