Impromidine

Impromidine (INN) is a highly potent and specific histamine H₂ receptor agonist.[1]

Impromidine

Clinical data
ATC code	none
Identifiers
IUPAC name 2-[3-(1H-imidazol-5-yl)propyl]-1-[2-[(5-methyl-1H-imidazol-4-yl)methylsulfanyl]ethyl]guanidine
CAS Number	55273-05-7
PubChem CID	41376
IUPHAR/BPS	1226
ChemSpider	37757
UNII	931L4X5WMM
ChEMBL	ChEMBL12608
CompTox Dashboard (EPA)	DTXSID90203780
Chemical and physical data
Formula	C14H23N7S
Molar mass	321.45 g·mol^−1
3D model (JSmol)	Interactive image
SMILES Cc1[nH]cnc1CSCCNC(=N)NCCCc2c[nH]cn2
InChI InChI=1S/C14H23N7S/c1-11-13(21-10-19-11)8-22-6-5-18-14(15)17-4-2-3-12-7-16-9-20-12/h7,9-10H,2-6,8H2,1H3,(H,16,20)(H,19,21)(H3,15,17,18) Key:MURRAGMMNAYLNA-UHFFFAOYSA-N
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It has been used diagnostically as a gastric secretion indicator.

See also

• Histamine agonists

References

1. Durant G, Duncan W, Ganellin C, Parsons M, Blakemore R, Rasmussen A (1978). "Impromidine (SK&F 92676) is a very potent and specific agonist for histamine H2 receptors". Nature. 276 (5686): 403–5. doi:10.1038/276403a0. PMID 714166.