Normethadone

Normethadone (INN, BAN; brand names Cophylac, Dacartil, Eucopon, Mepidon, Noramidone, Normedon, and others), also known as desmethylmethadone or phenyldimazone, is a synthetic opioid analgesic and antitussive agent. Normethadone is listed under the Single Convention on Narcotic Drugs 1961 and is a Schedule I Narcotic controlled substance in the United States, with a DEA ACSCN of 9635 and an annual manufacturing quota of 2 grams.[1] The salts in use are the hydrobromide (free base conversion ratio 0.785), hydrochloride (0.890), methyliodide (0.675), oxalate (0.766), picrate (0.563), and the 2,6-ditertbutylnapthalindisulphonate (0.480) [2]

Normethadone

Clinical data
Trade names	Cophylac
ATC code	R05DA06 (WHO)
Legal status
Legal status	AU: S9 (Prohibited substance) CA: Schedule I DE: Anlage III (Special prescription form required) US: Schedule I
Identifiers
IUPAC name 6-dimethylamino-4,4-diphenyl-hexan-3-one
CAS Number	467-85-6 847-84-7 (HCl)
PubChem CID	10090
ChemSpider	9687
UNII	KR2L2A68XL
KEGG	D07384
ChEMBL	ChEMBL346331
CompTox Dashboard (EPA)	DTXSID6057748
ECHA InfoCard	100.006.730
Chemical and physical data
Formula	C20H25NO
Molar mass	295.426 g·mol^−1
3D model (JSmol)	Interactive image
SMILES O=C(C(c1ccccc1)(c2ccccc2)CCN(C)C)CC
InChI InChI=1S/C20H25NO/c1-4-19(22)20(15-16-21(2)3,17-11-7-5-8-12-17)18-13-9-6-10-14-18/h5-14H,4,15-16H2,1-3H3 Key:WCJFBSYALHQBSK-UHFFFAOYSA-N
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See also

• Methade

References

1. http://www.deadiversion.usdoj.gov/fed_regs/quotas/2014/fr0825.htm
2. A-Z Encyclopaedia of Alcohol & Drug Abuse, pp 470