TSSK2

Testis-specific serine/threonine-protein kinase 2 is an enzyme that in humans is encoded by the TSSK2 gene.[5][6]

TSSK2
Identifiers
Aliases	TSSK2, DGS-G, SPOGA2, STK22B, TSK2, testis specific serine kinase 2
External IDs	OMIM: 610710 MGI: 1347559 HomoloGene: 31512 GeneCards: TSSK2
Gene location (Human) Chr. Chromosome 22 (human)[1] Band 22q11.21 Start 19,131,308 bp[1] End 19,132,622 bp[1]
Gene location (Mouse) Chr. Chromosome 16 (mouse)[2] Band 16 A3|16 11.09 cM Start 17,898,637 bp[2] End 17,900,024 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • transferase activity • nucleotide binding • protein kinase activity • metal ion binding • kinase activity • protein serine/threonine kinase activity • GO:0001948 protein binding • ATP binding • magnesium ion binding • GO:0032403 macromolecular complex binding Cellular component • cytoplasm • Acrosome • centriole • cytoskeleton • cell nucleus Biological process • cell differentiation • GO:0007243 intracellular signal transduction • phosphorylation • multicellular organism development • protein phosphorylation • spermatogenesis • spermatid development • autophosphorylation • peptidyl-serine phosphorylation Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	23617	22115
Ensembl	ENSG00000206203	ENSMUSG00000045521
UniProt	Q96PF2	O54863
RefSeq (mRNA)	NM_053006	NM_009436
RefSeq (protein)	NP_443732	NP_033462
Location (UCSC)	Chr 22: 19.13 – 19.13 Mb	Chr 16: 17.9 – 17.9 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000206203 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000045521 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Dunham I, Shimizu N, Roe BA, Chissoe S, Hunt AR, Collins JE, Bruskiewich R, Beare DM, Clamp M, Smink LJ, Ainscough R, Almeida JP, Babbage A, Bagguley C, Bailey J, Barlow K, Bates KN, Beasley O, Bird CP, Blakey S, Bridgeman AM, Buck D, Burgess J, Burrill WD, O'Brien KP (Dec 1999). "The DNA sequence of human chromosome 22". Nature. 402 (6761): 489–495. doi:10.1038/990031. PMID 10591208.
6. "Entrez Gene: TSSK2 testis-specific serine kinase 2".

Further reading

• Collins JE, Wright CL, Edwards CA, Davis MP, Grinham JA, Cole CG, Goward ME, Aguado B, Mallya M, Mokrab Y, Huckle EJ, Beare DM, Dunham I (2005). "A genome annotation-driven approach to cloning the human ORFeome". Genome Biol. 5 (10): R84. doi:10.1186/gb-2004-5-10-r84. PMC 545604. PMID 15461802.
• Hao Z, Jha KN, Kim YH, Vemuganti S, Westbrook VA, Chertihin O, Markgraf K, Flickinger CJ, Coppola M, Herr JC, Visconti PE (2005). "Expression analysis of the human testis-specific serine/threonine kinase (TSSK) homologues. A TSSK member is present in the equatorial segment of human sperm". Mol. Hum. Reprod. 10 (6): 433–444. doi:10.1093/molehr/gah052. PMID 15044604.
• Suzuki H, Fukunishi Y, Kagawa I, Saito R, Oda H, Endo T, Kondo S, Bono H, Okazaki Y, Hayashizaki Y (2001). "Protein-protein interaction panel using mouse full-length cDNAs". Genome Res. 11 (10): 1758–1765. doi:10.1101/gr.180101. PMC 311163. PMID 11591653.
• Kueng P, Nikolova Z, Djonov V, Hemphill A, Rohrbach V, Boehlen D, Zuercher G, Andres AC, Ziemiecki A (1998). "A novel family of serine/threonine kinases participating in spermiogenesis". J. Cell Biol. 139 (7): 1851–1859. doi:10.1083/jcb.139.7.1851. PMC 2132653. PMID 9412477.
• Gong W, Emanuel BS, Collins J, Kim DH, Wang Z, Chen F, Zhang G, Roe B, Budarf ML (1996). "A transcription map of the DiGeorge and velo-cardio-facial syndrome minimal critical region on 22q11". Hum. Mol. Genet. 5 (6): 789–800. CiteSeerX 10.1.1.539.9441. doi:10.1093/hmg/5.6.789. PMID 8776594.