UTP18

U3 small nucleolar RNA-associated protein 18 homolog is a protein that in humans is encoded by the UTP18 gene.[5][6][7][8]

UTP18
Identifiers
Aliases	UTP18, CGI-48, WDR50, small subunit processome component, UTP18 small subunit processome component
External IDs	OMIM: 612816 MGI: 1923402 HomoloGene: 41087 GeneCards: UTP18
Gene location (Human) Chr. Chromosome 17 (human)[1] Band 17q21.33 Start 51,260,546 bp[1] End 51,297,936 bp[1]
Gene location (Mouse) Chr. Chromosome 11 (mouse)[2] Band 11|11 D Start 93,859,243 bp[2] End 93,885,766 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • RNA binding Cellular component • Pwp2p-containing subcomplex of 90S preribosome • small-subunit processome • nucleolus • cell nucleus • nucleoplasm • not the membrane Biological process • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) • rRNA processing Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	51096	217109
Ensembl	ENSG00000011260	ENSMUSG00000054079
UniProt	Q9Y5J1	Q5SSI6
RefSeq (mRNA)	NM_016001	NM_001013375
RefSeq (protein)	NP_057085	NP_001013393
Location (UCSC)	Chr 17: 51.26 – 51.3 Mb	Chr 11: 93.86 – 93.89 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

See also

• Fibrillarin
• Small nucleolar RNA U3
• RCL1
• RRP9
• UTP11L
• UTP14A
• UTP15

References

1. GRCh38: Ensembl release 89: ENSG00000011260 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000054079 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Lai CH, Chou CY, Ch'ang LY, Liu CS, Lin W (Aug 2000). "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics". Genome Res. 10 (5): 703–13. doi:10.1101/gr.10.5.703. PMC 310876. PMID 10810093.
6. Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA (Jun 1996). "A "double adaptor" method for improved shotgun library construction". Anal Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.
7. Bernstein KA, Gallagher JE, Mitchell BM, Granneman S, Baserga SJ (Dec 2004). "The small-subunit processome is a ribosome assembly intermediate". Eukaryot Cell. 3 (6): 1619–26. doi:10.1128/EC.3.6.1619-1626.2004. PMC 539036. PMID 15590835.
8. "Entrez Gene: UTP18 UTP18, small subunit (SSU) processome component, homolog (yeast)".

Further reading

• Yu W, Andersson B, Worley KC, et al. (1997). "Large-scale concatenation cDNA sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.
• Scherl A, Couté Y, Déon C, et al. (2003). "Functional proteomic analysis of human nucleolus". Mol. Biol. Cell. 13 (11): 4100–9. doi:10.1091/mbc.E02-05-0271. PMC 133617. PMID 12429849.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Yokoyama A, Wang Z, Wysocka J, et al. (2004). "Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expression". Mol. Cell. Biol. 24 (13): 5639–49. doi:10.1128/MCB.24.13.5639-5649.2004. PMC 480881. PMID 15199122.
• Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243. S2CID 14294292.
• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.