Mycobacterium intermedium

Mycobacterium intermedium is a species of the phylum actinobacteria (Gram-positive bacteria with high guanine and cytosine content, one of the dominant phyla of all bacteria), belonging to the genus Mycobacterium.

Mycobacterium intermedium
Scientific classification
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M. intermedium
Binomial name
Mycobacterium intermedium
Meier et al. 1993, ATCC 51848

Etymology: Latin; intermedium, meaning between, rapidly and slowly growing mycobacteria.

Description

Gram-positive, and nonmotile acid-fast coccobacilli (2.0 µm x 2.6 µm).

Colony characteristics

  • Eugonic, smooth and photochromogenic colonies (3–5mm in diameter) on Löwenstein-Jensen medium.

Physiology

  • Growth on Löwenstein-Jensen medium at 22 °C, 31 °C, 37 °C and 41 °C, (optimal temperature between 31 °C and 37 °C), within 2–3 weeks.
  • Susceptible to ethambutol and rifampin.
  • Resistant to isoniazid and streptomycin.

Differential characteristics

  • Phylogenetic position between rapidly and slowly growing mycobacteria.
  • M. asiaticum is phenotypically very similar, but can be distinguished by its growth at 22 °C, and by its dysgonic growth.

Pathogenesis

Type strain

  • Repeatedly isolated from sputum from a patient with pulmonary disease.

Strain 1669/91 = ATCC 51848 = CCUG 37583 = CIP 104542 = DSM 44049 = JCM 13572

References

    • Meier et al. 1993. Mycobacterium intermedium sp. nov. Int. J. Syst. Bacteriol., 1993, 43, 204-209.


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