WNT8A

Protein Wnt-8a is a protein that in humans is encoded by the WNT8A gene.[5] Wnt8a may be involved in development of early embryos as well as germ cell tumors.[5]

WNT8A
Identifiers
Aliases	WNT8A, WNT8D, Wnt family member 8A
External IDs	OMIM: 606360 MGI: 107924 HomoloGene: 7553 GeneCards: WNT8A
Gene location (Human) Chr. Chromosome 5 (human)[1] Band 5q31.2 Start 138,083,990 bp[1] End 138,092,365 bp[1]
Gene location (Mouse) Chr. Chromosome 18 (mouse)[2] Band 18|18 B1 Start 34,542,313 bp[2] End 34,548,273 bp[2]
Gene ontology Molecular function • receptor binding • GO:0005110 frizzled binding • receptor ligand activity Cellular component • extracellular region • extracellular • extracellular matrix • collagen-containing extracellular matrix Biological process • canonical Wnt signaling pathway involved in neural crest cell differentiation • regulation of transcription involved in anterior/posterior axis specification • multicellular organism development • response to retinoic acid • neural crest cell fate commitment • neuron differentiation • canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment • beta-catenin destruction complex disassembly • Wnt signaling pathway • canonical Wnt signaling pathway • regulation of receptor activity • secondary palate development • cell fate commitment Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	7478	20890
Ensembl	ENSG00000061492	ENSMUSG00000012282
UniProt	Q9H1J5	Q64527
RefSeq (mRNA)	NM_001300938 NM_001300939 NM_031933 NM_058244	NM_009290
RefSeq (protein)	NP_001287867 NP_001287868 NP_490645	NP_033316
Location (UCSC)	Chr 5: 138.08 – 138.09 Mb	Chr 18: 34.54 – 34.55 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000061492 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000012282 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: Wnt8a wingless-type MMTV integration site family, member 8A".