Imidafenacin

Imidafenacin (INN) is a urinary antispasmodic of the anticholinergic class. Its molecular weight is 319.40 g/mol

Imidafenacin

Clinical data
Routes of administration	Oral
ATC code	none
Legal status
Legal status	In general: ℞ (Prescription only)
Identifiers
IUPAC name 4-(2-methyl-1H-imidazol-1-yl)-2,2-diphenylbutanamide
CAS Number	170105-16-5
PubChem CID	6433090
ChemSpider	4938278
UNII	XJR8Y07LJO
ChEMBL	ChEMBL53366
ECHA InfoCard	100.216.585
Chemical and physical data
Formula	C20H21N3O
Molar mass	319.40 g·mol^−1
3D model (JSmol)	Interactive image
SMILES CC1=NC=CN1CCC(C2=CC=CC=C2)(C3=CC=CC=C3)C(=O)N
InChI InChI=1S/C20H21N3O/c1-16-22-13-15-23(16)14-12-20(19(21)24,17-8-4-2-5-9-17)18-10-6-3-7-11-18/h2-11,13,15H,12,14H2,1H3,(H2,21,24) Key:SQKXYSGRELMAAU-UHFFFAOYSA-N
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References

• Kobayashi F, Yageta Y, Segawa M, Matsuzawa S (2007). "Effects of imidafenacin (KRP-197/ONO-8025), a new anti-cholinergic agent, on muscarinic acetylcholine receptors. High affinities for M3 and M1 receptor subtypes and selectivity for urinary bladder over salivary gland". Arzneimittelforschung. 57 (2): 92–100. doi:10.1055/s-0031-1296589. PMID 17396619.
• Miyachi H, Kiyota H, Uchiki H, Segawa M (June 1999). "Synthesis and antimuscarinic activity of a series of 4-(1-Imidazolyl)-2,2-diphenylbutyramides: discovery of potent and subtype-selective antimuscarinic agents". Bioorg. Med. Chem. 7 (6): 1151–61. doi:10.1016/S0968-0896(99)00003-6. PMID 10428387.