KIAA0157

BRISC complex subunit Abro1 is a protein that in humans is encoded by the FAM175B gene.[5][6]

ABRAXAS2
Identifiers
Aliases	ABRAXAS2, ABRO1, KIAA0157, FAM175B, family with sequence similarity 175 member B, abraxas 2, BRISC complex subunit
External IDs	OMIM: 611144 MGI: 1926116 HomoloGene: 12970 GeneCards: ABRAXAS2
Gene location (Human) Chr. Chromosome 10 (human)[1] Band 10q26.13 Start 124,801,819 bp[1] End 124,836,667 bp[1]
Gene location (Mouse) Chr. Chromosome 7 (mouse)[2] Band 7|7 F3 Start 132,859,225 bp[2] End 132,885,111 bp[2]
Gene ontology Molecular function • microtubule binding • polyubiquitin modification-dependent protein binding • GO:0001948 protein binding Cellular component • cytoplasm • centrosome • spindle pole • BRISC complex • spindle pole centrosome • midbody • microtubules • cytoskeleton • cell nucleus • microtubule minus-end • cytosol Biological process • chromosome segregation • cell division • mitotic spindle assembly • response to ischemia • protein K63-linked deubiquitination • cell cycle • attachment of spindle microtubules to kinetochore • protein deubiquitination • GO:0007067 mitotic cell cycle Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	23172	109359
Ensembl	ENSG00000165660	ENSMUSG00000030965
UniProt	Q15018	Q3TCJ1
RefSeq (mRNA)	NM_032182	NM_198017
RefSeq (protein)	NP_115558	NP_932134
Location (UCSC)	Chr 10: 124.8 – 124.84 Mb	Chr 7: 132.86 – 132.89 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000165660 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000030965 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Nagase T, Seki N, Tanaka A, Ishikawa K, Nomura N (Mar 1996). "Prediction of the coding sequences of unidentified human genes. IV. The coding sequences of 40 new genes (KIAA0121-KIAA0160) deduced by analysis of cDNA clones from human cell line KG-1". DNA Res. 2 (4): 167–74, 199–210. doi:10.1093/dnares/2.4.167. PMID 8590280.
6. "Entrez Gene: KIAA0157 KIAA0157".

Further reading

• Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.
• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.
• Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Colland F, Jacq X, Trouplin V, et al. (2004). "Functional proteomics mapping of a human signaling pathway". Genome Res. 14 (7): 1324–32. doi:10.1101/gr.2334104. PMC 442148. PMID 15231748.
• Brill LM, Salomon AR, Ficarro SB, et al. (2004). "Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry". Anal. Chem. 76 (10): 2763–72. doi:10.1021/ac035352d. PMID 15144186.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.